Protein Engineering Scientists (Oncology)- All Levels

Date Posted: 10/11/2018 Reference: VAC-1196237 Salary: £48000 Location: Abingdon Job type: Permanent Sector: Science | Speciality: Biotechnology Contact: Nathan Steels
Description

Protein Engineering Scientist(s), Oncology

We are looking for dedicated scientists, both senior and junior, to expand and strengthen our oncology protein engineering team. We are on the hunt for pragmatic, open-minded and collaborative bench scientists who are looking to contribute and grow in an open, team-oriented environment.

Associate Scientist: £21,000- £31,000
Scientist £27,000 - £39,000
Senior Scientist: £33,000 - £48,000

As a member of our Protein Science team you will be responsible for:

TCR and ImmTAC expression in E.coli, refolding and purification using chromatography methods
Analysing TCR and ImmTAC binding affinity and kinetics
Identifying TCRs from internally-generated phage libraries
Enhancing TCR affinity using our proprietary phage-display approach
Collaborating cross-functionally to develop and optimize ImmTAC drug candidates
Analysing and reporting experimental results verbally and in writing
To succeed in this role, you should have technical proficiency in the areas of protein biochemistry and molecular biology.

Essential skills include: protein expression in E.coli, chromatography-based protein purification (preferably using the AKTA system), SDS-PAGE, PCR, cloning, DNA sequence analysis and site-directed mutagenesis
Desirable skills include: DNA library construction/screening using phage display and analysis of protein interaction using BIAcore and Octet systems
You should have an advanced scientific degree, such as MSc or PhD in protein engineering/ biochemistry/ molecular biology or a related discipline.

This is an exciting time to join one of the UK’s leading biotechnology companies. We look forward to hearing from you!

Please note, sponsorship is not available for this role