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We found 204 job(s) for you:

  • Technical Manager - Sterile Processing

    Salary: £61000 Location: Oxford

    My Client is a leading gene and cell therapy company focused on developing life changing treatments for serious diseases. The client has undergone recent expansion and is currently hiring an experienced Technical Manager. They will provide both technical and scientific leadership within the department along with developing and maintaining relationships with key suppliers and technology providers. My Client is looking for an experienced Technical manager who has worked within a GMP environment and can support the activities within the MSAT function. The role will undertake and focus around sterile and aseptic processing for both third party clinical and commercial sterile manufacturing activities. . Key responsibilities and accountabilities: ? Provide technical and scientific leadership within OXB on aseptic processing and fill/finish activities for clinical and commercial manufacturing including technology transfer, technical troubleshooting, and continuous improvement of sterility assurance. ? Act as Subject Matter Expert (SME) utilising your technical competence and knowledge in aseptic processing, fill-finish, inspection and packaging to provide guidance on best practices to improve aseptic processes and procedures and maintain regulatory compliance. ? Generate and review documentation supporting technology transfer and New Product Introductions (NPI). Define appropriate success criteria for technical transfer and provide/document evaluation of the technical outcomes. ? Provide subject matter expertise (SME) within OXB on clean room technologies, single use systems and raw materials, design of process simulations (media fills), sterile manufacture. ? Extensive knowledge of the design, validation, operation and maintenance of the controlled environment including clean rooms, isolators, RABs, sterilisation processes, environmental monitoring and routine disinfection. Experience of manual and automated fill finish operations would be ideal. ? Experience in preparation for and participation in inspections (including FDA & MHRA) as well as performing focused GMP audits of sterile facilities. Person Specification: ? Bachelor degree (Masters/PhD/EngD preferred) or equivalent experience in a relevant science (e.g. Biological Sciences, Microbiology,) with substantial relevant experience in an industrial setting ? At least several years’ experience of working in multiple aseptic or sterile manufacturing facilities Salary: £56,000 - £61,000 This is a unique opportunity to join an ever-growing, organisation. Contact Robert Frame at NorthPoint Recruitment for immediate application.

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  • Data Engineer - Machine Learning Specialist

    Salary: £0 Location: Manchester

    We have an exciting opportunity based at an Intelligent Statistical Monitoring company based in Belgium, for an aspiring Data Scientist who wants to build a long-term career with a company, who shares their passion for innovation. Ideally suited to those who live and breath data, with a real emphasis on pushing the boundaries and wanting to understand new ways of working with machine learning and data engineering to ensure the best outcome for each project. This role will see you join the R&D team, in charge of Developing, Improving, Documenting and Maintaining new Data Mining Algorithms, with a focus on Machine Learning. If you’ve got between 1-3 years of development experience with Python or C++ in a Data Mining/Machine Learning position then this could be a great opportunity to further your career!

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  • Senior Data Scientist

    Salary: £100000 Location: Hasselt

    Based in Belgium our client are a small but cuttiong edge company based from offices in Hasselt in Belgium. They were formed 4 years ago, and offer machine learning solutions to the PCR analysis market; allowing companies to interpret PCR data at a higher accuracy, and decreased time compared to historical methods. As a data scientist, you will create the little pieces of intelligence that are plugged into the clients PCR workflow software platform. These so-called plugins are the beating heart of our product and consist of machine learned algorithms, specific molecular diagnostic information, and client-specific logic. You will focus on algorithm development, applying the latest machine learning techniques to interpret our biomedical data automatically. Besides that, you could take up a dataOps role. You optimize our process, spot efficiency gains and increase our throughput. The companies product is situated on the challenging crossroad between IT and biotechnology, directly aimed at laboratories and diagnostic test manufacturers within clinical, agricultural, companion, livestock & other diagnostics. We’re on a mission to improve the way data is analysed and are already working with industry-leading companies. Ideal candidates will have; + A master/ PhD degree in mathematical engineering and or computer science and you love data, especially lots of it. + You speak Matlab, a background in Python and/ or R is a plus. + You have a broad background and interest in all different techniques in artificial intelligence, you are experienced in using this knowledge to solve concrete business needs. + You are an expert when it comes to artificial intelligence and machine-learning. + You are familiar with or an expert in signal processing techniques. Our client have a stimulating startup atmosphere where you can grow your capabilities in an open and no-nonsense company culture. They want you to do the work you feel great at, or that you would like to become great at. They offer a fascinating role with continuous learning in an international environment where you will have the possibility to grow and shape a software solution right from the start. They combine state of the art data science with cutting edge technology in a streamlined development process to ensure we deliver only the best solutions to our customers. Salaries for the role are dependent on experience but are expected to be between 50-100k for the right candidates.

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  • C++ Developer

    Salary: £65000 Location: Walton-on-thames

    Based in Walton-On-Thames my client provide solutions and services for accurate static analysis, dataflow analysis and structural dependency analysis. They are considered pioneers in the industry and are true innovators. As a result of continued ambition and expansion they are actively seeking 5 C++ Developers. The successful candidate(s) will join a team of 20 developers and will enjoy a friendly, innovative and research focused group. The primary responsibility is developing code for projects from a technological perspective; ensuring that the code quality and software development life cycle activities are consistent with the company Standards and Quality procedures. Candidates should be passionate about creating commercially viable high performance technological solutions that meet the needs of demanding, large, global, multi-national customers. This job is part of a team of peers working on highly technical, software architecture initiatives. Job duties include, but are not limited to: research, tools evaluation, documenting patterns, design and standards, contributing into defining technology strategy, technology evaluation and recommendation, writing code for solutions. Competencies sought: + Considers C++ a core strength + Possesses Strong analytical skills + Competent in communication and presentation his/her knowledge to all relevant stakeholders; This invariably involves writing documentation and the communication and presentation of it. + Competent in understanding of the software development paradigms, methodologies and standards employed in the various industry sectors within which the organisation’s customers operate: automotive, aerospace, defence, telecoms and finance. + Able to ascertain and specify software quality attributes through the understanding of the organisations commercial goals, objectives, policies and strategies and to balance technical requirements with them. + Able to quickly understand functional requirements and technical designs that exhibit desired qualities in line with company policies, strategies and customer needs. + Competent to listen to criticism and be assertive in communicating and defending the integrity of projects in the face of vested interests and the ability to accept valid critiques. The successful candidate can expect a competitive salary which is dependent on experience but in the range of £30k - £65 per year (as the job is open to candidates of varying levels). The company also offer a very strong benefits package which includes health insurance, life insurance, great pension contributions and generous holidays. The company also offer regular opportunities for further career progression.

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  • Upstream Scientist

    Salary: £38000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are currently helping to resource for their upstream fermentaiton needs within their Process, R & D team. + To optimize upstream processes for producing lentiviral vectors, working within the Process R&D group. + Small scale and laboratory scale bioreactor cell culture activities for scale-up/scale-down of existing bioprocesses + Applying DoE methods to cell culture activities. PR&D works with the clients research teams involved in vector and cell engineering to ensure the seamless transfer of processes from research to manufacturing. The scope of work may include, but are not limited to vector purification, novel purifications, purification process development and verification, technology assessment, data analysis and project reporting. The individual must have a demonstrated ability to work independently and to manage multiple projects either through direct supervision or in collaboration with the programme team. The individual must be innovative and creative, show initiative, collaborative ability and have good general science management skills. Applicants are expected to have excellent time management skills, with the ability to adapt to rapid changes in projects priorities and meeting aggressive timelines. The individual should also enjoy working in a team setting and be able to work well with both research scientists and as well as external collaborators. Salaries for the position are expected to be in the 35-38k range.

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  • Software Engineer

    Salary: £0 Location: Leicester

    Software Engineer Overview A highly renowned organisation that promotes a creative and dynamic work environment is looking to recruit an experienced Software Engineer on a permanent basis in Leicester. This organisation produces market leading distribution and supply chain software products used by customers worldwide and is aiming for substantial growth in the next 5 years. Responsibilities After an initial training period, you will work within one of our Scrum development teams and report to a team leader. You will be responsible for development and design of code as well as maintenance and support of selected existing applications. As a Software Engineer, you will have: • Highest ethics and integrity. • A thorough understanding of Software Development methodologies and techniques. • Understanding of source code management systems. • Excellent analytical, organizational, and problem-solving skills, as well as a detail-oriented approach. • Excellent interpersonal and team playing skills. • Articulate with strong written and oral communication skills, both your colleagues and, later, customers at a non-technical level. • The discipline to meet strict deadlines. • Ability to self-learn (given suitable professional training). • Experience of working in a SCRUM team or other Agile development methods beneficial. Key Responsibilities: • Develop new and maintain existing features within the software products, working as part of a team within the Scrum development framework. • Maintain and improve code quality, development tools, and processes. • Work from user stories, user acceptance criteria, and test plans, following a test-driven development approach. • Present to and liaise with stakeholders during Sprint Reviews. • Create and maintain documentation. Key Experience Required: • Significant experience in software development. • Experience of working in a SCRUM team or other Agile development methods beneficial. • Knowledge and experience of Microsoft Visual Studio, Microsoft Team Foundation Server or similar tool set. • Knowledge or experience of working in, or systems/processes used in, a warehousing environment would be advantageous. Qualifications You will ideally hold a 2:1 BSc Honours Degree or above in Computer Science, Software Engineering or equivalent and already possess software development experience within industry. Knowledge and experience with the following technologies: • Unix/Linux/Windows. • Oracle Database Systems. • C Programming Language. • C# Programming Language. • Structured Query Language (SQL) including stored procedures, triggers etc. • Microsoft Visual Studio/.Net Framework. • Microsoft Team Foundation Server. • Some Knowledge of Visual Basic 6 and C++, for our legacy applications, would be beneficial. There will be occasions where you may need to visit and work on customer sites, both within the UK and internationally. After a period of training you should expect to also become involved in both the implementation and support of our systems, gaining exposure to the full software product lifecycle. This is a great opportunity to play a key role within a demanding and growing environment There are opportunities for career advancement within this thriving, award-winning professional organisation. Package Salary: £25k - £40k depending on skills and experience. 25 days’ holiday Workplace Pension Childcare Voucher Scheme Central Location Fast growing and market leading organisation with many opportunities for career progression

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  • Developer - Contract

    Salary: £0 Location: Gloucester

    Contract requirement for a Developer Summary The Developer is part of a team of Software Engineers working in an Agile/Scrum software development environment specializing in healthcare solutions based in Gloucestershire. The developer has a good level of both technical and business domain knowledge but may still specialise in a number of areas. They should be able to work in a fast-paced and demanding environment. Essential Duties and Responsibilities You will be working within a cross-functional Agile team which have the collective responsibility to deliver the business needs (roadmap) to the required schedule. This includes responsibility for writing, testing and maintaining code for the suite of software applications that complies with the quality standards of the organisation. Further the mentioned, there will be some requirement to undertake 3 -line support tasks, diagnosing and rectifying issues on customer systems. As such, good problem-solving skills and the ability to explain technical solutions clearly are important It is important that you remain aware of trends within the software development industry and must maintain a desire to continue to improve own knowledge and skills. Youll be able to effectively communicate in a clear, positive and professional manner to all levels from customers and peers to management level Education and/or Experience Must have experience Years of commercial experience with PHP (ideally most recent version), experience of working in an Agile environment, relational databases (MySQL / MS SQL Server) and front-end web technologies GIT (or other version control systems) Experience of modern frameworks (e.g. Laravel, Zend framework, jQuery, Bootstrap, Angular) Desirable experience Knowledge of the healthcare sector, including software products designed for clinical use Experience of JIRA, Confluence and Bitbucket or other Atlassian products PHP certification Containers and Docker Linux Graph Databases Composer and NPM API The Package You can expect a very competitive rate, an initial duration of 17 weeks, interesting and challenging work. In addition, the company in question are at the forefront of their sector, with this position promising to look very good on the CV and with a good chance of extensions.

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  • Senior / Principal / Lead MSAT Scientist. Contract

    Salary: £0 Location: Oxford

    Senior/Principal /Technical Lead Scientist/Engineer (MSAT). Contract. Oxford My client, a globally renowned Gene Therapy are under going a phase of expansion. As part of this, they require support in Manufacturing Sciences and Technology team. There are currently 3 open positions for Contract MSAT Scientists/Engineers. Company and Team Overview An exceptional company with over 20 years’ experience in Gene and Cell therapy. True pioneers in the field, they were the first organisation to treat humans through in vivo lentiviral based vectors. This MSAT team is involved in all aspects of clinical and commercial manufacturing carried out either in-house or by third party CMO’s on behalf of the company. Job Overview ? Provide technical and scientific leadership to clinical and commercial manufacturing on-site and third party CMO sites including technology transfer, technical troubleshooting, complex deviation investigations, change control, and continuous improvement. ? Perform root cause investigations using a systematic approach to resolve complex problems and lead multidisciplinary teams in developing and implementing solutions. ? Gather, evaluate and analyse complex process data for all products and sites for manufacturing process robustness and capability via ongoing process verification. ? Partnering with other functions to ensure scale-up is robust and scientifically sound leading to consistent performance Key Responsibilities and Accountabilities ? The successful candidate will be an influential MSAT representative within the organisation working across multiple projects at different stages of the commercial lifecycle. ? Lead cross-functional activities working across Research, Process R&D, Manufacturing, Supply Chain and Quality Groups. ? Technical reviewer of manufacturing documentation (batch manufacturing records, deviation handling, CAPA, change controls, SOPs, etc.) ? Responsible for internal documentation to ensure quality and compliance required for regulatory submissions. ? Generate and review documentation supporting technology transfer and NPI. Define success criteria for technical transfer and provide expert evaluation of the technical outcomes. ? Help to build and maintain a process-specific knowledge database for technology transfer, NPI and process stewardship; identify continuous improvement activities to improve performance. ? Develop relationships with suppliers and service providers ? Provide guidance on process transfer and support activities to junior members of the team. Key Skills and Requirements ? Process development or GMP production experience preferred. ? Experience in aseptic processing and/or fill & finish would be an advantage. ? Proven influencing skills at all levels of the company across multiple project teams. ? As a person in plant, provide technical support and training of manufacturing personnel to improve understanding of cell culture, purification and fill & finish operations across the manufacturing sites. ? Expertise in the use / application of variety of problem solving tools and quality risk assessment methodologies would be ideal. *Travel may be required in support of tech transfer activities. Person Specification ? Minimum post-graduate degree in Biology/Biochemistry, Chemical/Biochemical Engineering or a related field with a minimum of 5+ years of industrial experience. ? Alternatively, a candidate with extensive industrial experience in Biologics (7 years+), ideally within a GMP regulated environment. ? Demonstrated interpersonal skills with ability to work cross-functionally both with internal and external partners. ? Excellent communication skills to gain internal company support and influence external CMOs at all levels. ? Good time management and experience of dealing with conflicting priorities and multiple tasks. ? An interest in operational excellence is desirable. ? Knowledge of Microsoft Office Suite is required; preferably with data base development experience. ? Experience in process automation and software solutions would also be an advantage. The Package The successful candidates can expect a generous hourly rate and significant length of contract. In addition, this is an excellent opportunity to join a real player in the Gene Therapy sector and a chance to gain referrals, recommendations and build reputation.

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  • Deep Learning Researcher

    Salary: £45000 Location: Oxford

    Based in Oxford, my client are a leading medical imaging technlology company who are looking for a first-class medical imaging researcher to join their technology team, developing cutting-edge image processing and deep learning algorithms to improve acute stroke diagnosis. You will take a leading role in researching the fundamental science and algorithms that contribute to the company’s core IP. This is an exciting opportunity to bring the latest medical imaging research into real-world use. You must have an excellent understanding of state of the art medical imaging technology, with a PhD in a relevant research area, or otherwise demonstrate outstanding research ability. Recent work with contrast and non-contrast CT, or MRI image analysis would be particularly desirable, especially in brain imaging or stroke-related fields. Other skills we are looking for include: + A good core knowledge of computer vision and image processing algorithms, particularly filtering, image registration and classification techniques. + Experience with developing deep learning algorithms for image analysis + Active participation in the medical imaging research community + Programming expertise in Python + An ability to clearly communicate complex ideas and systems, both to technical colleagues (e.g. software developers) and non-technical audiences, both verbally and through graphical or textual content + An ability to generate creative ideas and solutions to real-world problems, based on a deep understanding of the problem domain + Data science skills, including data preparation, cleaning, and scripting You will be given a significant share of responsibility for the underlying technology behind my clients products, and you should be able to work independently on complex problems. However, team members are expected to work together to find elegant solutions to issues from all areas of the company, so clear communication is vital.

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  • Scientist (Bioinformatics – NGS Data Analysis)

    Salary: £38000 Location: Oxford

    The company I am hiring for is a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a focus on viral vectors for gene therapy applications. I am looking for an experienced and self-motivated bioinformatician to design, implement and run software pipelines for analysing next-generation sequencing (NGS) data. The successful applicant will be located within purpose-fitted laboratories at the Oxford Science Park. ***What the Bioinformatician will do*** + Build state-of-the-art data processing pipelines for targeted re-sequencing, whole genome sequencing, genome editing, and differential expression analysis experiments + Support our wet lab scientists in the planning, and interpretation, evaluation and visualisation of results for investigations with an NGS component + Stay up-to-date with new developments, technologies and methods in NGS data analysis, and proactively seek out collaborations with our group leaders to develop and extend our intellectual property portfolio in this area ***What the Bioinformatician will need*** + MSc/BSc in bioinformatics, computational biology, computer science or a related field, or equivalent experience in a biotechnology research environment + Programming experience with one or more of Python, Perl, Java and R, and familiarity with associated numerical analysis libraries (e.g. NumPy for Python, ND4J for Java, ect.) + Analysis experience with NGS datasets (preferably Illumina paired-end, PacBio or Nanopore) in DNA-seq, RNA-seq, break-seq, GUIDE-seq or similar contexts ***What the Bioinformatician will need get*** + Competitive Salary up to £38,000 + Work in state-of-the-art facility and sector + Excellent benefits & training opportunities If this sounds like the perfect role for you, then please get I touch today!

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