Jobs

We found 257 job(s) for you:

  • Scientist – Lentiviral vectors

    Salary: £38000 Location: Oxford

    My client are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. We are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of our development as a company. The Scientist – Lentiviral Vectors will be involved in a range of internal platform development and commercial projects, predominantly focused on Lentiviral vector engineering, and establishing stable viral packaging cell lines and associated processes. They have a number of on-going programmes and collaborations in this area, and multiple government supported grant awards, which the recipient will contribute towards. Scientist colleagues are expected to drive and lead specific projects and areas of research from the bench, while providing support and training to technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Candidates should have; + PhD/DPhil in relevant discipline, or MSc with significant experience (>4 years) + Experience working in a commercial/industry environment is preferred but not essential + Extensive track record of handling a range of adherent and suspension mammalian cell lines + Knowledge and experience of viral vector engineering, production and characterisation, with a focus on Lentivirus + Good experience with analytical techniques including flow cytometry and qPCR Salaries are expected to be around the 28-38k mark.

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  • Scientist- AAV Production

    Salary: £38000 Location: Oxford

    Based in Oxford my client who are a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. We are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are currently looking for a scientist in their AAV Production team who will manage an internal function for the generation and characterisation of AAV vectors for both in-vitro and in-vivo applications (non-GMP). The appointee would work to expand this service within the company and would then be responsible for its operational delivery working with technician colleagues. This function would sit within the AAV Vector Group, which addresses both viral vector engineering and novel-bioproduction methodologies and works with a number of academic and industry collaborators. Candidate should have the following skills; + Prior experience in generating and characterising AAV vectors is essential. + Relevant techniques (see next section) include plasmid preparation, transfection (hyperflask/stack, cell factories, suspension), harvest/clarification, purification by iodixanol, CsCl, affinity, IEX, and characterisation by qPCR, ELISA, Western blot. Salaries are expected to be in the 35-38k range.

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  • QC Senior Technologist

    Salary: £34000 Location: Salisbury

    My client is a fast-growing biopharmaceuticals company based in the South-West of England. Experts in developmental production and the bringing to market of biologicals, my client have decades of experience in production, characterisation, process and analytical validation of life saving biopharmaceuticals, including the Anthrax Vaccine. Taking on the mantle of QC Senior technologist will see you reporting directly to the QC Analytical Manager. You will be tasked to manage and perform the transfer/validation of analytical methods from Development into a GMP environment in QC Analytical Services (QCAS). The role involves all activities involved in transferring analytical methods from Development to QCAS, including running analytical methods in both Development and QCAS, writing transfer/validation protocols, executing protocols in the laboratory, writing up the associated transfer/validation reports, performing release analysis and training existing members of staff in transferred methods. Are you prepared to begin a new chapter in your career? If so, this could be the role for you.

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  • Quality Systems Officer

    Salary: £35000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit an experienced Quality Systems Officer for their quality department. Candidate should have the following skills and experience; + Minimum of 3 years working within a GMP pharmeuticals environment. + Solid working knowledge of validation and quality management systems. + Experience conducting quality based audits, investigations and root cause analysis. + Experience of document control and/or records management. + Strong team skills Salaries for the role are expected to be around the 35k mark.

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  • Validation Specialist

    Salary: £45000 Location: Oxford

    I am currently recruiting for a Validation Specialist to join a world-renowned biopharmaceutical company; this company specialises in developing innovative gene-based medicine and therapeutic vaccines. This exciting about has come about due to the year-on-year growth and are now in a position to bring a talented Validation Specialist to join the team in their Oxford based site. This person will support GMP manufacturing and laboratory facilities by ensuring all aspects of validation (manufacturing & laboratory equipment, facilities and utilities qualification and routine requalification activities, cleaning validation, computerised systems validation and process validation) are complete and up to date. The Validation Team also represent the business in customer audits and regulatory inspections to demonstrate compliant systems. + Ensure compliance with regulatory requirements and Quality Management System by supporting/assisting Validation Manager in performing and managing qualification and validation studies of GxP critical systems, equipment and processes. + Generate validation documentation including master plans, validation assessments and test protocols; execute qualification/validation protocols/studies + Ensure Validation Department provides timely, appropriate and expert advice on qualification and validation issues to Manufacturing, QC/QA & Engineering and other company functions as required + Supporting the validation of equipment, facilities, utilities and processes in accordance with GMP requirements and a lifecycle approach in coordination with multi-functional Validation + Represent the Validation Department during client audits and regulatory inspections ***What the Validation Specialist needs*** + Demonstrable validation experience in a biopharmaceutical, pharmaceutical or related industry including Manufacturing/Laboratory Equipment, Facilities & Utilities Qualification (URS, DQ, IQ, OQ & PQ) + Broad knowledge of biopharmaceutical and pharmaceutical industry regulations and guidelines including GMP, GDP, GLP, GEP + Experience of aseptic processing and cleanrooms highly desirable + Computer Systems Validation (CSV) would be advantageous + Educated to degree level in Science (Biological) ***What the Validation Specialist will get*** + Competitive salary + excellent benefits + Work in a fantastic state-of-the-art facility + Lots of training and development opportunities If this sounds like the perfect role for you, then please get in touch today!

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  • Senior Downstream Processing Scientist

    Salary: £45000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are currently helping them to recruit a senior downstream scientist within their process, research and development team. Candidates will be recognized experts in downstream processing including bioprocess design, protein expression and purification. They will be primarily involved in purifying and characterizing a variety of therapeutic candidates in support of projects from early stage research to pre-clinical programs. Process, Research and Development works with the companies research teams involved in vector and cell engineering to ensure the seamless transfer of processes from research to manufacturing. The scope of work may include, but are not limited to vector purification, novel purifications, purification process development and verification, technology assessment, data analysis and project reporting. The individual must have a demonstrated ability to work independently and to manage multiple projects either through direct supervision or in collaboration with the programme team. The individual must be innovative and creative, show initiative, collaborative ability and have good general science management skills. Applicants are expected to have excellent time management skills, with the ability to adapt to rapid changes in projects priorities and meeting aggressive timelines. The individual should also enjoy working in a team setting and be able to work well with both research scientists and as well as external collaborators. Salaries for the senior downstream processing roles are expected to be in the 40 to 45k range.

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  • Analytical Scientist (PR&D)

    Salary: £38000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit an analytical scientist within their process, research and development team. Candidates should have the following skills and experiences; + An undergraduate degree (or equivalent-level qualification) in a Life Sciences or Biotechnology-related subject + Good aseptic techniques + Knowledge of general cellular and molecular biology laboratory techniques + Practical experience of a range of bioprocess analytical techniques (such as cell-based assays, FACS based assays, nucleic acid extractions, qPCR, SDS PAGE, Western blot analysis, ELISA, HPLC, etc.) + The ability to work in a high paced team environment and to, meet challenging deadlines + Demonstrated ability to work independently as well as in a team setting + Strong written and verbal skills Salaries are expected to be in the 35-38k range.

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  • Senior Analytical Scientist in Process, Research and Development

    Salary: £42000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit a senior analytical scientist for their process, research and development department. Candidates should have experience with the following; + Bsc in Life-sciences or biotechnology related subject. + Strong aseptic techniques + Knowledge of general cellular, and molecular biology techniques + Practical experience of a range of bio-process analytical techniques such as cell based assays, FACS, nucleic acid extractions qPCR, SDS< Western blot, ELISA + Strong written and verbal skills Salaries for the roles are expected to be in the 38-42k range.

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  • Innovation Officer

    Salary: £45000 Location: Cambridge

    Based in Cambridgeshire my client is a leading biotech company specialising in Gene editing platform technology. Due to expansion they are currently looking to take on an Innovations Officer to join a diverse and energetic team. You will be responsible for liaising with the company on matters of technology transfer, IP and Patent searches. You must be approachable, friendly and have a confident manner. Ideally you will have; + PhD in Life Sciences subject (i.e Biology, Genetics, Virology, Immunology, bioinformatics etc) + Knowledge of technology transfer and Patent Searches + Basic understanding of IP The company offers great career progression and a starting salary around the £45k mark.

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  • Senior Scientist (ADG)

    Salary: £37500 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit a senior scientist within their ADG team. Candidates should have the following skills and experiences; + Minimum BSc Degree in Life Sciences/Science/Analytical Science or equivalent level qualification in these disciplines + A good research and development background in quantitative PCR and/or protein analysis. + Practical industry experience in analytics and development projects/activities + Experience of working in GMP-like environments + Use of automation in qPCR work flows. + Development and improvement of analytical methods for lentiviral characterization + A strong background in assay development and automation + Good level of communication and presentation skills + Demonstrated ability to work independently as well as in a team + Ability to undertake projects to agreed timelines and adapt to rapid changes in project priorities Salaries are expected to be in the 35-38k range.

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