Jobs

We found 197 job(s) for you:

  • Senior Viral Vector Scientist

    Salary: £46000 Location: London

    The Client My client, based in London, are specialists in helping Cell and Gene therapy companies translate early stage research into quality, commercially viable, scalable and investable therapies. With a team of over 120 Cell and Gene therapy experts and state-of-the-art development and viral vector labs, my client has ensured they remain a Centre of Excellence in this field. Purpose of Role: The purpose of this role is to provide expertise in the execution of viral vector industrialisation projects. The viral vector strategy will focus on the use of industrial bioprocessing techniques such as bioreactors and chromatography, to ensure supply of these critical materials for in vivo and ex vivo cell therapies. Key Accountabilities: Delivery of viral vector process and analytical development projects through technical oversight of project, working with the Lead Scientist on experimental design and execution. Particular focus upon downstream process operations, including unit operations from harvest to final fill Assist with costing of proposals for partners and support of BD function during new project scoping by providing technical support activities. Strong interaction with the Tech Transfer function and Project Managers to enable the development and tech transfer of viral vector processes. Strong Interaction with academic and industry based groups to provide engineering solutions for vector cell line development, upstream and downstream bioprocessing Generating manufacturing and development protocols in relation in vivo and ex vivo gene therapy products to support technology development and regulatory submissions Author GM Risk Assessments when requested and support GMSO. Maintain general laboratory cleanliness, Health and Safety and GXP standards, where appropriate Experience Experience of upstream and downstream bioprocessing of viral vectors including viral vector biology and cell line development. Experience or know how of working with GMP regulations to manufacture viral vectors, cell therapies or other biologics. Experience of cell culture of human and/or mammalian cell lines is essential. Experience in the development of analytical assays suitable for use as characterisation, QC release methods and in-process controls is desirable. Experience of tech transfer to/from commercial and research organisations Experience of viral vectors used in the ex vivo and in vivo modification of products is essential. Experience of working closely with BD and partners to plan, cost and secure projects. Experience in QMS is highly desirable. Experience in writing and carrying out GMP production protocols is desirable. Experience of delivering on agreed commercial objectives For more information please contact Robert Frame on: robert.frame@wearenorthpoint.co.uk or 0161 504 8058

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  • Front End Engineer

    Salary: £0 Location: Oxford

    My client empowers scientists and clinicians with tools that enable them to take their research to the next level. With first in class imaging capabilities, their imager is capable of taking images and videos of living cells and tissue, and zooming all the way down to the bottom where we can see individual molecules do their job that enable life as we know it. tools. Located in Oxford (UK) and Palo Alto (CA, USA). Founded in 2016, they have grown rapidly to a team represented by over 25 nationalities. All disciplines from the sciences, engineering, business to humanities are well represented in this diverse, dynamic, and mission-driven team. Deriving great energy from working towards a common goal of bringing to people tools that make science better, and genuinely making difference at the end of the day. Now they need you to join us on this journey. Responsibilities This role is part of a fast-moving software team focused on developing novel applications using distributed systems. The team will take on challenging problems involving large datasets and complex interactions on the cloud. Career progression is limited only by your own motivation and capabilities. They actively encourage their team members to become involved in many aspects of this young business to gain a fully rounded set of skills. • Extensive CSS and JS experience using Angular, React or VueJs • HTML/CSS experience, including concepts like layout, and accessibility • Experience with browser APIs and optimizing front end performance • Experience working closely with designers throughout the development process, iterating quickly on designs to achieve the best possible outcome • Strong attention to detail and desire to get the little details just right ----- This role presents an opportunity to work alongside some of the industries most talented developers, supporting technology that will surely change the way in which we see the world. If you are looking to take the next step in your career and you have a passion for enabling a brighter future for the world we live in, this could be the perfect opportunity for you. Please contact Kieran Whittaker for a private and confidential discussion on: - Tel: 0161 504 2203 Email: kieran.whittaker@wearenorthpoint.com

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  • DevOps Engineer

    Salary: £50000 Location: Oxford

    I am currently looking for an DevOps Engineer to work with a company that although in size is moving away from its Start-up nature, but still maintains its Start-up atmosphere. The company specialises in scientific imagining, given the strength of the products they have they have received a number of different invests, and have grown from a work force of 15 to 90 with a view to double this by this time next year. This role is part of a fast-moving software team focused on developing novel applications using distributed systems. The team will take on challenging problems involving large datasets and complex interactions on the cloud. You will be working to accelerate development of our projects by building a solid foundation of infrastructure appropriate to progressive stages of scale. Career progression is limited only by your own motivation and capabilities. We actively encourage our team members to become involved in many aspects of this young business to gain a fully rounded set of skills. ***What the What the DevOps Engineer needs*** + Experience writing scripts in one or more languages such as Python + Advanced Linux skills + Experience with building out scalable and automated Cloud platforms on AWS + Experience building and maintaining CI/CD pipelines + Understanding of scalable networks ***What the What the DevOps Engineer will get*** + Salary up to £50,000 + excellent benefits including bonus and free lunch + Work in a fantastic state-of-the-art facility + Lots of training and development opportunities If this sounds like the perfect role for you, then please get in touch today!

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  • IT Engineer

    Salary: £35000 Location: Oxford

    I am currently looking for an IT Engineer to work with a company that although in size is moving away from its Start-up nature, but still maintains its Start-up atmosphere. The company specialises in scientific imagining, given the strength of the products they have they have received a number of different invests, and have grown from a work force of 15 to 90 with a view to double this by this time next year. Due to the nature of the role I need somebody who can hit the ground running and can take on the existing IT requirements. In the short term this will be installing new hardware and software, setting up accounts for company employees, dealing with accounts for leavers, and trouble shooting. However, the company is growing rapidly and will soon be opening an office in the US, and later in other locations worldwide. We can see that the IT needs will grow rapidly as will your opportunity within the company. ***What the IT Engineer will do*** + Maintaining the IT Infrastructure + Installation of Hardware & Software + Exchange and AD management + Maintaining a Linux server environment with Microsoft applications ***What the What the IT Engineer will do needs*** + Proven industry experience working a diverse IT role + Linux server experience + Microsoft Exchange / Active Directory + Desirable experience – Jira/Confluence/Scripting ***What the What the IT Engineer will get*** + Salary up to £35,000 + excellent benefits including bonus and free lunch + Work in a fantastic state-of-the-art facility + Lots of training and development opportunities If this sounds like the perfect role for you, then please get in touch today!

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  • Application Scientist

    Salary: £40000 Location: Oxford

    I have an exciting opportunity to join a forward-thinking organisation who are pioneering the latest and greatest Super-Resolution Fluorescent Microscopes. My client is now looking to grow their company and create a centre of excellence for manufacturing and engineering and create a multi-disciplinary environment with a blend of intelligent experts from a variety of disciplines. I have a number of exciting opportunities for those who are ambitious, capable and ready to join a multi-disciplinary team, working with autonomy and confidence. Primary responsibilities of an Application Scientist are to support both commercial and technical development within the business. This role is an important lynchpin in our growing business, and application scientists will be expected to contribute their technical knowledge to a variety of roles in the company. If you want to join a team who are influencing the way in which we see the world, this could be the opportunity for you. For more information please contact Robert Frame on 0161 923 8189 or robert.frame@wearenorthpoint.com

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  • Optical Research and Development Scientist

    Salary: £40000 Location: Oxford

    I have an exciting opportunity to join a forward-thinking organisation who are pioneering the latest and greatest Super-Resolution Fluorescent Microscopes. My client is now looking to grow their company and create a centre of excellence for manufacturing and engineering and create a multi-disciplinary environment with a blend of intelligent experts from a variety of disciplines. I have a number of exciting opportunities for those who are ambitious, capable and ready to join a multi-disciplinary team, working with autonomy and confidence. I am looking for optical research and development scientists who will be working on exciting projects focusing on biological and medical imaging and involve using skills such as programming, data analysis and optical instrumentation. Looking forward, the role will require effective interfacing with all the other functions at the company, including Production, Software, Data Analysis, and Applications. Having complete accountability day-to-day for setting up, organizing and performing experiments, as well as designing and building instrumentation for imaging and extensive microscopy experience. If you want to join a team who are influencing the way in which we see the world, this could be the opportunity for you. For more information please contact Robert Frame on 0161 923 8189 or robert.frame@wearenorthpoint.com

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  • Technology Development Scientist

    Salary: £0 Location: Oxford

    I have an incredible opportunity to join a Teal organisation who are pioneering the latest and greatest Super-Resolution Fluorescent Microscopes. My client has made huge waves in the industry and were founded on the back of Nobel Prize winning research. They’re now looking to grow their company and have a number of exciting opportunities for those who are ready and capable of joining a multi-disciplinary team, working with autonomy and confidence. I am looking for an ambitious, organised and hardworking molecular biologists or biochemists to develop single-molecule applications - novel biochemical methods to work with my clients state-of-the-art microscopy system. You will be part of a nascent research activity, imagining, creating and following through on clever new ideas. You will be responsible for designing, performing and analysing new assays that use the microscope in clever ways to explore biological samples of interest. Having complete accountability day-to-day for setting up, organizing and performing experiments, as well as analysing, organising and reporting on the data produced and participating in team meetings, strategy discussions and journal clubs. If you want to join a team who are literally changing the way in which we see the world, this could be the opportunity for you. For more information and a confidential discussion, please contact me on: - Tel: 0161 923 8174 Email: kieran.whttaker@wearenorthpoint.co.uk

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  • AR VR Design Engineers

    Salary: £65000 Location: Oxford

    My Client is looking to expand their design capability with a motivated individual looking for a challenge. The candidate has the opportunity to join a high-performance R&D team, engaged in designing custom adjustable optics for major global companies. The Design Engineer will be part of a cross-functional team, responsible for the design, CAD, prototyping and early stage process engineering for the optical elements of 3rd party AR / VR applications. This is a customer facing role and requires excellent communication and presentation skills. The ideal candidate should have experience of designing precision plastic components, complex mechanisms with electronic actuation and control, and optical components will be a distinct advantage. Key Responsibilities and Accountabilities Product / Component Concept and Design • Leadership of problem analysis, ideation, evaluation and appropriate research • Concept development through to implementation of inventive design solutions • Detail design with proficient knowledge of appropriate manufacturing processes • High standard of engineering work, design control, robust design, tolerance stack analysis, design for manufacture, design for assembly, input into DFMEA’s Design in 3D CAD (primarily Solidworks) • Use of skeleton model for common reference geometry • Understanding and creation of complex CAD model set-ups • Appreciation of minute factors & general sound modelling principles • Ability to work methodically, consistently & transparently (esp. within CAD) • Following good practice for drawing and data management systems

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  • French Speaking Project Manager

    Salary: £0 Location: Basingstoke

    Project Manager: Basingstoke Owing to continued ambition, my client, a pioneering FinTech business with a global presence, are actively seeking a Project Manager. Purpose of the Job The purpose of this role is to provide project management for the implementation of solutions (hardware & software) to commercial banks, cash in transit companies and central banks. This position will use best practices in project management to plan, execute, track & report on projects. A technical background is required to effectively communicate with the team, assess progress, understand technical decisions and how they affect the project. Qualifications and Experience - Fluent in English and French (written and oral) - Experience in project management (Software and/or Hardware) implementation into customer production environments - PRINCE2 or PMP qualification preferred - Good knowledge of MS Office, MS Project and Visio - Experience of delivering high value concurrent projects in a project management or implementation position - Experience of managing concurrent high-value profile customer projects - Experience of managing third party suppliers - Competent in process analysis and risk management (assessment/mitigation) - Experience in project financial tracking i.e. budget control / forecasting / invoicing Key Activities The successful candidate will work as part of a team but will take ownership for individual clients and projects therein. The projects themselves are in essence about the implementation of an Enterprise Cash Management suite of software products. Please note that given the Global nature of the business, international travel is required as part of the Project Management team. Subset Activities of this overarching goal include - Agree specifications and project plans with customers. - Hold regular progress meetings with the customer, issuing weekly internal project reports detailing progress/risks/cash flow etc. - Manage customer relationships at all levels to ensure full satisfaction with performance from formal contract signed-off through delivery and services supplied to post project review meetings - Ensure best practice is followed by assisting and guiding project teams in selling scope - Follow agreed methodologies irrespective of client/customer discipline or lack thereof To have a detailed knowledge of the contract and the solution to be implemented, and to be the main point of contact both internally and externally on all project issues - To ensure that the projects are delivered in the timescale agreed with the customer, within the cost estimated and that all activities over and above the contract requirements are agreed with and invoiced to the customer - Work with internal release management to keep apprised of changes and upcoming developments in the ECM software applications - Work with Engineering and Production teams (in Dallas) to keep apprised of changes and upcoming developments of new technology - Ensure smooth post implementation hand-over to Services and Support The Package The successful candidate can expect a competitive starting salary, excellent benefits which include 26 days holiday (34 including bank), life insurance and health insurance. In addition, there is free on-site parking and perks such as subsidised Gym memberships.

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  • Senior Scientist - DMPK

    Salary: £0 Location: Slough

    Berkshire- Senior Scientist – DMPK- Permanent My client is a global biopharmaceutical company focused on drug discovery for the treatment of severe diseases, affecting the immune and central nervous systems. Due to a fantastic period of continued growth they are currently looking for senior DMPK scientist to work within the iADME group responsible for DMPK input to both NCE and NBE projects from early discovery to submission. This role is a lab-based position and requires the right candidate to make expert opinions on in vitro DMPK issues and translation to in vivo as well as to humans. The role will champion and develop new scientific strategic directions and guides or contributes to development of new assays. You will have: Ideal candidate will be educated to PhD level (or equivalent) with postdoc/ industrial experience or MSc or BSc (or equivalent) with extensive experience in DMPK. Strong Knowledge of pharmacokinetic concepts is essential, and experience in a variety of DMPK assays and techniques (in vitro, ex vivo and in vivo) is preferred. Fantastic salary (depending on experience) Great development options Chance to be part of a multinational company with global opportunities

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