Jobs

We found 394 job(s) for you:

  • Scientist (Bioinformatics – Genome Editing)

    Salary: £38000 Location: Oxford

    My client, a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. They are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of their development as a company. My client seeks an enthusiastic and self-starting bioinformatician to design, implement and evaluate novel software tools to support their genome editing group. In particular, the successful applicant will train machine learning models to predict the targeting patterns of CRISPR/Cas9 gRNAs. The successful applicant will join their interdisciplinary bioinformatics team, working alongside scientific programmers, infrastructure engineers, and web app developers to support both commercial and R&D projects. No prior experience of working with CRISPR/Cas9 is needed. Key Responsibilities + Work with the genome editing team and NGS specialists to develop a framework for reliably evaluating the targeting patterns of CRISPR/Cas9 gRNA libraries. + Apply state-of-the-art data science and statistical learning techniques to derive gRNA suitability/fitness rule-sets from the in-house CRISPR/Cas9 NGS datasets. + Engineer user-friendly software tools to facilitate CRISPR/Cas9 gRNA library design against new targets; work closely with the in-house software engineers to integrate interfaces for these into the web-based LIMS. + Stay up-to-date with new developments, technologies and methods in genome editing, and proactively seek out collaborations with their group leaders to develop and extend our intellectual property portfolio in this area. + Carry out any other duties commensurate with the grading of this post, as required. Salary is negotiable on experience.

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  • Validation Manager

    Salary: £65000 Location: OXFORD

    Validation Manager (permanent)- Oxford- Biotech- up to £65k Based in Oxfordshire, my client is a world leader in Gene and Cell Therapy technologies. Due to a fantastic period of growth they have an exciting opportunity for a motivated individual to join and lead the validation department as a Validation Manager. You will be responsible for acting as the subject matter expert and supporting the GMP manufacturing facilities by managing and coordinating all aspects of validation (equipment & facilities qualification and routine requalification activities, cleaning validation, computerised systems validation and process validation) and overseeing the Validation Team. Key skills and requirements: You will have: BSc in life sciences or another relevant subject Significant validation experience within a GMP environment Valid UK Driving License Significant team management experience. Proven problem-solving skills/diagnosing faults/resolving qualification issues. Competitive Salary Fantastic development opportunities Great Career progression

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  • 3rd Line Engineer

    Salary: £37000 Location: Wetherby

    I am currently recruiting for a reputable solutions provider based just outside of Leeds, this company has been established for over 30 years with a company portfolio of over 250 companies. The role I am recruiting for is a 3rd Line Technical Consultant, this person is pivotal to the company and will be the within a team of 4 that are the 1st point of call when it comes to projects, and the last line of defence when it comes to technical issues. **What the 3rd Line Technical Consultant will need*** + MCSE 2012 & expert level experience within the Microsoft server environment + End-to-end experience with VMware (preferably VCP level) + Solid infrastructure deployment experience + Good understanding of networking principals + Excellent with documentation and sharing best practice ***What the 3rd Line Technical Consultant will get*** + Competitive salary up to £40,000 + Excellent project pipeline + Paid training (MCSE/VCP/CCNA) + Great benefits package ***PLEASE NOTE: SC Clearance must be achieved for this post*** If this sounds like the prefect role for you then please get in touch today!

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  • Design Engineer

    Salary: £50000 Location: Oxford

    We are currently recruiting for a Design Engineer, the company is based in Oxford. They are a global leader in design and production of adjustable focus eyewear. The company was founded back in 2005, since that time they’ve grown from 2 people to nearly 60 with sites in the UK, Tokyo & Boston. The Design Engineer will be responsible for managing the design process for a number of components and sub-assemblies, from specification review and concepting to prototype release; including production and testing of prototypes and development of the prototype manufacturing process flow and Design for Manufacture (DfM) activities. The role therefore requires close and efficient coordination with the process team operating the product prototyping line and liaison with third party suppliers of materials, sub-components and equipment. The product design challenge will require working with precision components to tight tolerances. Experience of designing with rubbers & plastics, fluid & membranes, ultrasonic welding and / or optical components will be a distinct advantage. ***What the Design Engineer will do*** + Concept and detailed implementation of inventive design solutions + Detail design with integration of the appropriate manufacturing processes + High standard of engineering work, design control, robust design, tolerance stack analysis, design for manufacture, input into DFMEA’s (design failure mode and effect analysis) + Close working with manufacturing team to produce holistic design solutions ***What the Design Engineer needs*** + Must be an experienced designer / engineer, possessing excellent written and oral communication skills (5+ years) + Understanding of complex Solidworks CAD model set-ups + Bachelors / Masters Degree in a Mechanical Engineering, Product Design or a related subject + Working in accordance to ISO 13485, MDD and FDA 21 CFR regulations preferred but not essential ***What the Design Engineer will get*** + Salary up to £50,000 + excellent benefits + Work in a fantastic state-of-the-art facility If this sounds like the perfect role for you, then please get in touch today!

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  • JavaScript Developer

    Salary: £55000 Location: RUNCORN

    I am currently recruiting for a JavaScript Developer; this person will be working for a cutting-edge data management software house based in Runcorn. The company have a unique proprietary piece of software, focused on data management that improves customer service at the same time as delivering operational efficiencies for many organisations across different industry sectors. ***What the Senior JavaScript Developer will do*** + Mix of both greenfield development and continuous improvement for the company’s software + Independent worker capable of showing initiative but with a proven ability to work collaboratively as part of a Software Development team + Mentor and support less experienced team members + Work on connecting the front-end JS to the back-end Java platform ***What the JavaScript Developer needs*** + Experience with Both JavaScript & Java + Familiarity with REST or JSON + Ideally some experience with HTML5/React/Angular ***What the JavaScript Developer will get*** + Competitive salary up to £65,000 + excellent benefits + Lots of training and development opportunities If this sounds like the perfect role for you, then please get in touch today!

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  • Process Compliance Officer

    Salary: £40000 Location: OXFORD

    Process Compliance Officer Based in Oxfordshire, my client is a world leader in Gene and Cell Therapy technologies. Due to a fantastic period of growth they have an exciting opportunity for a motivated individual to join the manufacturing department in the role of Process Compliance Officer. As a Process Compliance Officer, you will work alongside the GMP Manufacturing teams to ensure the timely completion of batch related issues, as well as ensuring compliance with internal and external GMP requirements. Including leading investigations and root cause analysis into process and facility deviations, CAPAs and non-conformances with in a GMP, pharma/ Bio tech industry. You will have: Experience of working within a GMP manufacturing environment Experience with Manufacturing documentation such as SOPs, Deviations, Change Controls Risk Assessments and CAPAs Familiarity with Root Cause Analysis techniques and the ability to amalgamate and interpret complex data in an investigative capacity would be an advantage Competitive salary Excellent benefits

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  • Electro-Mechanical Design Engineer

    Salary: £50000 Location: Oxford

    We are currently recruiting for a Design Engineer, the company is based in Oxford. They are a global leader in design and production of adjustable focus eyewear. The company was founded back in 2005, since that time they’ve grown from 2 people to nearly 60 with sites in the UK, Tokyo & Boston. The Design Engineer will be part of a cross-functional team, responsible for the CAD, prototyping and early stage process engineering for the optical module of 3rd party VR/ AR applications. This is a customer facing role and requires excellent communication and presentation skills. The Design Engineer will be responsible for managing the design process for a number of components and sub-assemblies, from specification review and concepting to prototype release; including production and testing of prototypes and suppporting development of the manufacturing process to full scale production. The role therefore requires close and efficient coordination with the manufacturing team and liaison with third party suppliers of materials, sub-components and equipment. Candidates should have the following experience; + Must be an experienced designer / engineer, possessing excellent written and oral communication skills (5+ years) + Working in a high-tech multidisciplinary environments; experience of customer-facing engineering consultancy an advantage + Managing suppliers + Working in accordance to ISO 13485, MDD and FDA 21 CFR regulations preferred but not essential. + Bachelors / Masters Degree in a Mechanical Engineering, Product Design or a related subject. Salaries for the role are expected to be around £50k.

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  • QMS and Compliance Lead

    Salary: £0 Location: SALISBURY

    Focused on curing the worlds deadliest diseases, this pioneering biopharma is now seeking a QMS and Compliance Lead to join their team on a fixed term basis. Acting as QMS and Compliance Lead will see you at the helm of a Cross Disciplined team, delivering compliant Quality Systems and developing an industry leading QMS. Other duties include: • To keep up to date with the requirements of the Medicines Authorities across the EU and rest of world (where relevant) • Provide oversight and direction to development and GCP teams to enable new products to be brought to market. • To provide input and leadership with the Quality Management System (QMS) within the business to drive simple compliant systems. • Assistance with regulatory inspections and client audits. • To promote and uphold the highest standards of professionalism in order to create, maintain and enhance the reputation of the business, amongst its customers and stakeholders both nationally and internationally • To review company Project Files (PSFs, commercial project files etc) to ensure compliance with the current regulatory requirements and company procedures. • To deliver continuous improvement in all areas of the business to enhance the quality, delivery, rate of growth and competitiveness • To liaise and interact positively with appropriate regulatory authorities to ensure company compliance This is a fantastic opportunity and an opportunity to join a team where you can be proud to be producing life-saving products that really make a difference. The company boasts flexible working hours, innovative projects and an incomparably intelligent team to work alongside.

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  • Regulatory Affairs Officer

    Salary: £35000 Location: Borehamwood

    Based in Hertfordshire, my client manufactures a wide range of plasma-derived therapeutic products which are distributed to over 40 countries worldwide. They are committed to supporting both healthcare professionals and providing a continuous supply of reliable, high quality, life saving products to patients on a 24/7, 365 day a year basis, and have a vibrant 60-year heritage and is currently embarking on an ambitious programme of investment in research, technology and manufacturing methods to grow the business significantly over the next few years. They are currently recruiting for a number of positions and are interested specfically in receiving applications from qualified regulatory affairs officers with the following skills; + Min of 3 years experience in a Regulatory Affairs function + Solid experience with licencing activities in Middle East countries, South America and Asia. + Knowledge of generation and maintenance of Company Core Safety Information (CCSI) + Experience with the end-to-end procedure for generation of drug labels and maintaining compliant drug labels in the UK and 'rest of world markets' + Experience of dealing directly with Health Authority assessors, in particular the MHRA. + Demonstrated effective communication and collaboration with agents and distributors in 'rest of the world 'countries. + Knowledge of current legislation and guidance related to labelling of medicinal products. + Knowledge or experience of generating eCTD documentation packages, in particular Module 1 Salaries are dependent on experience.

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  • Product Manager

    Salary: £50000 Location: Wokingham

    Based in Wokingham my client designs and delivers labelling solutions for organizations that need complete product auto-identification and lifecycle traceability. With the continual tightening of labelling regulations and audits, they empower their clients to safeguard their reputation by ensuring compliance, and significantly reduce costs by eliminating recalls through labelling errors. They are the market leader in world-class label lifecycle management, and is trusted for delivering personalized service excellence to clients in varied sectors including medical device, life sciences, healthcare, automotive, chemical and manufacturing. Based in the global headquarters, the product management function is responsible for managing the end-to-end lifecycle of the product portfolio. The Product Manager will take responsibility for understanding specific market sectors, industry drivers or opportunities, and for developing strategies to address these effectively. These will usually comprise the development of new or existing software products and propositions. The Product Manager will be responsible for ensuring market and customer requirements are captured and documented accurately, and for conveying the prioritised requirements effectively to the Development team. They will lead virtual teams in the design, costing, development and market launch of these software products, being responsible for bringing these to market on time and budget. Salary is negotiable on experience.

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