Jobs

We found 303 job(s) for you:

  • Senior Viral Vector Scientist

    Salary: £46000 Location: London

    The Client My client, based in London, are specialists in helping Cell and Gene therapy companies translate early stage research into quality, commercially viable, scalable and investable therapies. With a team of over 120 Cell and Gene therapy experts and state-of-the-art development and viral vector labs, my client has ensured they remain a Centre of Excellence in this field. Purpose of Role: The purpose of this role is to provide expertise in the execution of viral vector industrialisation projects. The viral vector strategy will focus on the use of industrial bioprocessing techniques such as bioreactors and chromatography, to ensure supply of these critical materials for in vivo and ex vivo cell therapies. Key Accountabilities: Delivery of viral vector process and analytical development projects through technical oversight of project, working with the Lead Scientist on experimental design and execution. Particular focus upon downstream process operations, including unit operations from harvest to final fill Assist with costing of proposals for partners and support of BD function during new project scoping by providing technical support activities. Strong interaction with the Tech Transfer function and Project Managers to enable the development and tech transfer of viral vector processes. Strong Interaction with academic and industry based groups to provide engineering solutions for vector cell line development, upstream and downstream bioprocessing Generating manufacturing and development protocols in relation in vivo and ex vivo gene therapy products to support technology development and regulatory submissions Author GM Risk Assessments when requested and support GMSO. Maintain general laboratory cleanliness, Health and Safety and GXP standards, where appropriate Experience Experience of upstream and downstream bioprocessing of viral vectors including viral vector biology and cell line development. Experience or know how of working with GMP regulations to manufacture viral vectors, cell therapies or other biologics. Experience of cell culture of human and/or mammalian cell lines is essential. Experience in the development of analytical assays suitable for use as characterisation, QC release methods and in-process controls is desirable. Experience of tech transfer to/from commercial and research organisations Experience of viral vectors used in the ex vivo and in vivo modification of products is essential. Experience of working closely with BD and partners to plan, cost and secure projects. Experience in QMS is highly desirable. Experience in writing and carrying out GMP production protocols is desirable. Experience of delivering on agreed commercial objectives For more information please contact Robert Frame on: robert.frame@wearenorthpoint.co.uk or 0161 504 8058

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  • Lentiviral Vector Scientist

    Salary: £38000 Location: Oxford

    My client is a leading gene engineering company who are pioneering technologies that streamline the biopharmaceutical design, discovery and development process of viral solutions, gene editing solutions and antibody solutions. My client is looking to add talented scientists to their lentiviral vector group as they look to build their expertise over the next 12 months in the viral therpaeutics field. CRITERIA: • BSc/MSc in Biology, Biochemistry, Genetics or related field, with >2 years relevant experience or Ph.D with >1 year relevant experience • Experience working in a commercial/industry environment is preferred but not essential. Essential: • Extensive track record of handling a range of adherent and suspension mammalian cell lines. • Knowledge and experience of viral vector engineering, production and characterisation, with a focus on Lentivirus. • Good experience with analytical techniques including flow cytometry and qPCR. • Ability to independently analyse, interpret and present scientific data in a clear manner. • Good communication and inter-personal skills. • Strong ability to multi-task under pressure. For more information on the above position, please contact Robert Frame on 0161 504 8058 or robert.frame@wearenorthpoint.co.uk

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  • Computer Vision & AI Developer

    Salary: £0 Location: France

    I’m representing a pioneering company based in France who specialise in the production of sustainable, premium Proteins for use in Aquaculture and pet nutrition. With global population on the rise and an expected 70% Human food calorie gap by 2050, my client is working against the clock to create a cleantech, sustainable alternative to traditional nutritional methods. Due to continued success and the recent opening of a first-of-its-kind new facility, my client is looking to expand. They are currently looking for a Computer Vision/AI developer to work on developing, improving and extending their characterisation software. Responsibilities As a Computer Vision & AI specialist, you will be tasked with discovering optimal tools for visual data acquisition and processing. You will train algorithms to recognise and extract features from images, enabling classification based on pattern recognition of known characteristics whilst proposing new classifications based on new characteristics. This role will provide you with the opportunity to work on the full scope of the project, from the acquisition of data processing tools, analysis, through to implementation. You will work closely with both Operators and Quality Control team members, as well as with those responsible for the rearing and breeding, in order to identify features and translate them into data form. You will then work to build autonomous processes to enable the integration of existing data collection, with the data collected by the image analysis. Skills • Knowledge of statistical languages, and their data processing / formatting modules • Knowledge of statistical image processing techniques (using open source tools) • Good communication skills, including written, common use of the Office Pack (MS Office Pack) • Basic theoretical knowledge or affinity with life sciences • Affinity with intellectual work • Autonomy, good interpersonal skills, initiative, taste for experimentation and teamwork • English spoken and written • French or other language ----- This role presents an opportunity to get in on the ground floor of a great Computer Vision & AI team within a company which has received multiple awards, including being voted 1 of the top 100 Cleantech companies in 2018. If you are looking to take the next step in your career in computer vision and you have a passion for enabling a brighter future for the world we live in, this could be the perfect opportunity for you. Please contact Kieran Whittaker for a private and confidential discussion on: - Tel: 0161 504 2203 Email: kieran.whittaker@wearenorthpoint.com

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  • Process Engineer

    Salary: £0 Location: Salisbury

    My Client is a leading manufacturer of biopharmaceutical products and with a rich history of pharmaceutical development in vaccines and therapeutics they are looking for an outstanding process engineer to join their team. The Process Engineer is the System technical expert for all Engineering Utilities systems within the GMP Envelope, and is responsible for the identification of and managing small projects relating to the utilities systems and interfacing with the wider Pharmaceutical Engineering group to ensure Utilities systems within the GMP envelope remain compliant with current Good Manufacturing Practice. Roles and Responsibilities To monitor Utilities equipment trend data as provided by the computerised maintenance management system and liaison with the maintenance teams/users, to recommend and manage process improvements/initiatives and when required prepare justifications for submission within the appropriate capital budget. ? Project Manage small business critical GMP projects as delegated by the Process Engineering Manager in accordance with the GMP Capital Project procedure. ? Represent the Engineering function at BSI, MHRA and FDA audits as subject matter expert for Utilities supported by the Process Engineering Manager. ? To be responsible for the writing, and review of User Requirement specifications, SOP’s, and generation of design documentation related to Utilities systems and other equipment within the GMP envelope. ? Review and Approval of Engineering technical regulatory documents as required to support the Engineering function including review and approval of Safety related documents such as pressure systems written schemes of examination. For more information please contact Robert Frame on: 0161 504 8058 or robert.frame@wearenorthpoint.com

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  • Front End Engineer

    Salary: £0 Location: Oxford

    My client empowers scientists and clinicians with tools that enable them to take their research to the next level. With first in class imaging capabilities, their imager is capable of taking images and videos of living cells and tissue, and zooming all the way down to the bottom where we can see individual molecules do their job that enable life as we know it. tools. Located in Oxford (UK) and Palo Alto (CA, USA). Founded in 2016, they have grown rapidly to a team represented by over 25 nationalities. All disciplines from the sciences, engineering, business to humanities are well represented in this diverse, dynamic, and mission-driven team. Deriving great energy from working towards a common goal of bringing to people tools that make science better, and genuinely making difference at the end of the day. Now they need you to join us on this journey. Responsibilities This role is part of a fast-moving software team focused on developing novel applications using distributed systems. The team will take on challenging problems involving large datasets and complex interactions on the cloud. Career progression is limited only by your own motivation and capabilities. They actively encourage their team members to become involved in many aspects of this young business to gain a fully rounded set of skills. • Extensive CSS and JS experience using Angular, React or VueJs • HTML/CSS experience, including concepts like layout, and accessibility • Experience with browser APIs and optimizing front end performance • Experience working closely with designers throughout the development process, iterating quickly on designs to achieve the best possible outcome • Strong attention to detail and desire to get the little details just right ----- This role presents an opportunity to work alongside some of the industries most talented developers, supporting technology that will surely change the way in which we see the world. If you are looking to take the next step in your career and you have a passion for enabling a brighter future for the world we live in, this could be the perfect opportunity for you. Please contact Kieran Whittaker for a private and confidential discussion on: - Tel: 0161 504 2203 Email: kieran.whittaker@wearenorthpoint.com

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  • DevOps Engineer

    Salary: £50000 Location: Oxford

    I am currently looking for an DevOps Engineer to work with a company that although in size is moving away from its Start-up nature, but still maintains its Start-up atmosphere. The company specialises in scientific imagining, given the strength of the products they have they have received a number of different invests, and have grown from a work force of 15 to 90 with a view to double this by this time next year. This role is part of a fast-moving software team focused on developing novel applications using distributed systems. The team will take on challenging problems involving large datasets and complex interactions on the cloud. You will be working to accelerate development of our projects by building a solid foundation of infrastructure appropriate to progressive stages of scale. Career progression is limited only by your own motivation and capabilities. We actively encourage our team members to become involved in many aspects of this young business to gain a fully rounded set of skills. ***What the What the DevOps Engineer needs*** + Experience writing scripts in one or more languages such as Python + Advanced Linux skills + Experience with building out scalable and automated Cloud platforms on AWS + Experience building and maintaining CI/CD pipelines + Understanding of scalable networks ***What the What the DevOps Engineer will get*** + Salary up to £50,000 + excellent benefits including bonus and free lunch + Work in a fantastic state-of-the-art facility + Lots of training and development opportunities If this sounds like the perfect role for you, then please get in touch today!

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  • IT Engineer

    Salary: £35000 Location: Oxford

    I am currently looking for an IT Engineer to work with a company that although in size is moving away from its Start-up nature, but still maintains its Start-up atmosphere. The company specialises in scientific imagining, given the strength of the products they have they have received a number of different invests, and have grown from a work force of 15 to 90 with a view to double this by this time next year. Due to the nature of the role I need somebody who can hit the ground running and can take on the existing IT requirements. In the short term this will be installing new hardware and software, setting up accounts for company employees, dealing with accounts for leavers, and trouble shooting. However, the company is growing rapidly and will soon be opening an office in the US, and later in other locations worldwide. We can see that the IT needs will grow rapidly as will your opportunity within the company. ***What the IT Engineer will do*** + Maintaining the IT Infrastructure + Installation of Hardware & Software + Exchange and AD management + Maintaining a Linux server environment with Microsoft applications ***What the What the IT Engineer will do needs*** + Proven industry experience working a diverse IT role + Linux server experience + Microsoft Exchange / Active Directory + Desirable experience – Jira/Confluence/Scripting ***What the What the IT Engineer will get*** + Salary up to £35,000 + excellent benefits including bonus and free lunch + Work in a fantastic state-of-the-art facility + Lots of training and development opportunities If this sounds like the perfect role for you, then please get in touch today!

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  • Protein Engineering Scientists (Oncology)- All Levels

    Salary: £48000 Location: Abingdon

    Protein Engineering Scientist(s), Oncology We are looking for dedicated scientists, both senior and junior, to expand and strengthen our oncology protein engineering team. We are on the hunt for pragmatic, open-minded and collaborative bench scientists who are looking to contribute and grow in an open, team-oriented environment. Associate Scientist: £21,000- £31,000 Scientist £27,000 - £39,000 Senior Scientist: £33,000 - £48,000 As a member of our Protein Science team you will be responsible for: TCR and ImmTAC expression in E.coli, refolding and purification using chromatography methods Analysing TCR and ImmTAC binding affinity and kinetics Identifying TCRs from internally-generated phage libraries Enhancing TCR affinity using our proprietary phage-display approach Collaborating cross-functionally to develop and optimize ImmTAC drug candidates Analysing and reporting experimental results verbally and in writing To succeed in this role, you should have technical proficiency in the areas of protein biochemistry and molecular biology. Essential skills include: protein expression in E.coli, chromatography-based protein purification (preferably using the AKTA system), SDS-PAGE, PCR, cloning, DNA sequence analysis and site-directed mutagenesis Desirable skills include: DNA library construction/screening using phage display and analysis of protein interaction using BIAcore and Octet systems You should have an advanced scientific degree, such as MSc or PhD in protein engineering/ biochemistry/ molecular biology or a related discipline. This is an exciting time to join one of the UK’s leading biotechnology companies. We look forward to hearing from you! Please note, sponsorship is not available for this role

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  • Embedded Application Developer

    Salary: £55000 Location: London

    I am currently recruiting for Application Developer (Embedded) in London, working for a globally recognised brand in the trading sector. This position will require someone whos able to use their own initiative, but equally work comfortably within a team of developers & traders. You will be working in the Risk team, involving a mixture of trading, energy supply and of course IT applications. The team you will be working with is split over 2 locations in London & Germany. This post sits with a team in London, but will require working closely with the other teams and occasional travel to Germany. ***What Application Developer (Embedded) will do*** + Provide Support & development to the Risk in their daily risk reporting tasks, for several bespoke applications + MicroStrategy support and development + Excel & VBA support + Requirements gathering for and development of applications within an ‘embedded team’ ***What the Application Developer (Embedded) Needs*** + Excellent blend of experience of both .Net & Excel + Very strong with MicroStrategy (9.4.1 or higher) + Solid appreciation of data warehousing and BI + Beneficial experience would be (dimensional modelling, SQL, Oracle, JIRA) *** What the Application Developer (Embedded) will get*** + Competitive salary up to £55,000 + Discretionary bonus paid annually + Excellent benefits package including family health cover, gym, pension and childcare vouchers + Excellent working environment where development is encouraged If this sounds like the perfect role for you, then please do get in touch today!

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  • Application Developer

    Salary: £65000 Location: London

    I am currently recruiting for Application Developer in London, working for a globally recognised brand in the trading sector. This position will require someone whos able to use their own initiative, but equally work comfortably within a team of developers & traders. You will be working in one of the most interesting business units, involving a mixture of trading, energy supply and of course IT applications. The team you will be working with is split over 4 locations in London, Germany, Singapore and Swindon – This post sits alone in London, but will require working closely with the other teams and occasional travel to Germany. ***What Application Developer will do*** + Support, maintain & enhance the application of the market data IT Solutions Team + Interact closely with different business areas to solve production issues + Attaching new market data sources to the data platform + Analyse new business requirements & implement specialised software solutions ***What the Application Developer Needs*** + Excellent blend of experience of both VBA/VB6 and C# + Very strong with database structures and Query production with Oracle & SQL + Good experience in JavaScript, TypeScript and application development + Experience in Agile software development (Kanban, Scrum) *** What the Application Developer will get*** + Competitive salary up to £65,000 + Discretionary bonus paid annually + Excellent benefits package including family health cover, gym, pension and childcare vouchers + Excellent working environment where development is encouraged If this sounds like the perfect role for you, then please do get in touch today!

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