Biotechnology

  • Group Leader within AAV Vectors 5/23/2018 12:00:00 AM

    Salary: £60000 Location: Oxford

    Based in Oxford our client is a leader in synthetic biology and are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. They are recruiting for a large number of positions at present and are interested in qualified candidates to fill their group leader role within the AAV vectors division. The Group Leader will be involved in a range of internal platform development and commercial projects, predominantly focused on establishing novel AAV vectors, stable viral packaging cell lines/bioproduction systems, and running a commercial batch production function through a sub-team. The company have a number of on-going programmes and collaborations in this area, and multiple government supported grant awards, which the recipient will contribute towards. Prior experience in engineering AAV vectors is essential, as is a detailed knowledge of AAV vector biology, production and characterisation methodologies. Group Leaders are expected to take a scientific and technical leadership role, while providing support and training to Scientists and technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Candidate should have experience in the following; + PhD/DPhil in relevant discipline, with significant experience (>4 years) + Experience working in a commercial/industry environment is preferred but not essential + Demonstrated people management ability, through supervision and development of junior colleagues + Strong network within AAV research and/or commercial arena + Extensive track record of handling a range of adherent and suspension mammalian cell lines + High-level knowledge and experience of viral vector engineering, production and characterisation, with a focus on AAV + Good experience with analytical techniques including flow cytometry/FACS, qPCR, ELISA, HPLC Salaries for the role are expected to be in the 50-65k range.

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  • Associate Scientist in Antibody Discovery 5/23/2018 12:00:00 AM

    Salary: £27000 Location: Oxford

    Based in Oxford our client is a leader in synthetic biology and are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. They are recruiting for a large number of positions at present and are interested in qualified candidates to fill their group leader role within the AAV vectors division. The Associate Scientist will be involved in a range of internal platform development and commercial projects, predominantly focused on expanding antibody discovery technologies and platforms. My client has several on-going programmes in this area, and multiple government supported grant awards, towards which the recipient will contribute. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Prior experience in generating antibody candidates from libraries, particularly in the context of mammalian display is particularly desirable, as is subsequent expression, characterisation and profiling of lead molecules. Salaries are expected to be in the 25 to 28k range dependent on experience.

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  • Downstream Process Scientist 5/23/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit a downstream scientist within their process, research and development team. +Candidates will be recognized experts in downstream processing including bioprocess design, protein expression and purification. +They will be primarily involved in purifying and characterizing a variety of therapeutic candidates in support of projects from early stage research to pre-clinical programs. PR&D works with the clients research teams involved in vector and cell engineering to ensure the seamless transfer of processes from research to manufacturing. The scope of work may include, but are not limited to vector purification, novel purifications, purification process development and verification, technology assessment, data analysis and project reporting. The individual must have a demonstrated ability to work independently and to manage multiple projects either through direct supervision or in collaboration with the programme team. The individual must be innovative and creative, show initiative, collaborative ability and have good general science management skills. Applicants are expected to have excellent time management skills, with the ability to adapt to rapid changes in projects priorities and meeting aggressive timelines. The individual should also enjoy working in a team setting and be able to work well with both research scientists and as well as external collaborators. Salaries for the position are expected to be in the 35-38k range.

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  • QA Officer 5/23/2018 12:00:00 AM

    Salary: £35000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit a QA Officer for their quality department. Candidate should have the following skills; + 3 years experience working within pharmaceutical QA + Quailty investigations and root cause analysis + change control + Exposure to MHRA and customer/client inspections + Working knowledge og GMP and quality related pharma regulations + Document control and experience using EDMS Salaries for the position are expected to be in the 35k range.

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  • Senior Microbiologist 5/23/2018 12:00:00 AM

    Salary: £33000 Location: Warrington

    My client is a fast growing microbiological services company, and is recruiting for a Senior Microbiologist/Virologist to join its rapidly expanding and dynamic team. The post holder will enable the delivery of microbiological services to current and prospective clients, on time and on budget. As a customer focussed company, our client needs to maintain a high level of professionalism and timeliness and this role will help in delivering on those aims. The post holder will work within a dynamic and enthusiastic microbiological team. The successful individual will support the laboratory team. They will be involved in the provision of staff training in line with internal SOPs and will support other Senior Microbiologists and Laboratory Microbiologists to deliver projects in line with client requirements. The post holder will check reports written by other staff. The post holder will provide key scientific support to the Laboratory Manager and Microbiologists. The post holder will present data/information/reports at appropriate meetings. The successful candidate will be involved in research and development programmes that support the service side of the business. The post holder may be required to produce scientific literature and present data at conferences and client meetings throughout the UK and abroad. Quality Salaries are expected to be in the 26-33k range.

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  • Scientist- Gene Editing 5/23/2018 12:00:00 AM

    Salary: £0 Location: SOUTH WEST

    Based in Oxford, our client is a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. They are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are currently in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of their development as a company. The Gene Editing Scientist will be involved in a range of internal platform development and commercial projects, predominantly focused on expanding gene editing capabilities and platforms. My client has a number of on-going programmes in this area, and multiple government supported grant awards, which the recipient will contribute towards. Scientist colleagues are expected to drive and lead specific projects and areas of research from the bench, while providing support and training to Technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. KEY RESPONSIBILITIES: •Work closely with internal and external stakeholders to define project goals and deliverables, in line the planned project objectives •To keep up to date with the scientific literature and developments in the field •Set an example to other colleagues, and to train junior staff in appropriate techniques •Provide project summaries and reporting, as required •Promote and suggest implementation of new methods, technologies and processes to ensure best practice •Support line manager with customer interactions, and in ensuring smooth running of the group •To adhere strictly to established quality standards, essential for on-going activities •Provide accurate record keeping at all times MINIMUM QUALIFICATIONS OR EXPERIENCE NEEDED: •Msc or PhD/DPhil in relevant discipline (MSc should be associated with minimum 2-3 years relevant laboratory experience) •Experience of using gene editing platforms (including CRISPR) •Experience working in a commercial/industry setting is preferred but not essential •Extensive mammalian cell culture experience Salaries are expected to be in the 35-40k range.

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  • QC Technologist 5/23/2018 12:00:00 AM

    Salary: £25000 Location: Salisbury

    My client is a leading developer and manufacturer of life saving pharmaceutical therapeutics and vaccines. The client performs a range of breakthrough production, quality and development roles within the pharmaceutical production process. The client is now looking to strengthen their quality control unit by hiring a QC Technologist who will play an incremental part in the company’s strategy. The role will centre around the microbiological QC analyses to support the client’s production and validation programmes. The client is looking for an effective communicator who has GMP experience and can work to a high standard in a microbiology environment. The candidate would ideally need to be highly organised as well as the ability to work within a team. Pharmaceutical industry experience is desirable. Salary: £22,000 - £25,000 Pension scheme 30 days annual leave This is a fantastic opportunity to join a unique company that strives for breakthrough results.

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  • Head of Bioinformatics 5/22/2018 12:00:00 AM

    Salary: £90000 Location: MANCHESTER

    Based in Manchester, my client helps world-leading research companies & scientists solve the most difficult biomedical challenges of today. Their technology uses AI and human biomedical expertise to tie together mostly unused sources of knowledge (‘dark data’) to enrich our understanding of biomedicine. We are a small, but growing team and are searching for extremely talented individuals who’ll join us in our mission. You will have years of top experience working as a bioinformatician, most likely after completing a PhD, although this could have been gained from a commercial setting. Most importantly, you must demonstrate that you’re either at or approaching the peak of your career and are ready to apply these skills in a challenging environment where your work will have a direct impact on our success. Candidates must have most of the following; + Are an expert problem solver, with a strong portfolio of existing research. + Are driven by a desire for quality, pragmatic, a continuous learner & critical thinker. + Have vast experience of one of systems biology, network biology and drug discovery + Are stats mad, with the ability to use R, Matlab or any other popular statistics platform. + Proficient at script writing (Python etc.). We have a separate software engineering team. + Comfortable writing and assisting with grants and publications. + Are able to design research projects from scratch. We love to experiment. Perks: + Competitive pay. We have a large ceiling for top applicants. + Options (employee share scheme). + Talented team to work alongside. + Located in the Manchester Science Park with excellent inner and outer city transport links. + Broad, modern tech stack. + Ability to work with some of the world’s leading biomedical research companies to drive the development of the therapeutics of the future. + Creativity & innovation strongly encouraged & rewarded. + Recent investment, clear roadmap and highly motivating work with an opportunity to make a real difference to biomedical developments.

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  • Validation Specialist 5/22/2018 12:00:00 AM

    Salary: £45000 Location: OXFORD

    I am currently recruiting for a Validation Specialist to join a world-renowned biopharmaceutical company; this company specialises in developing innovative gene-based medicine and therapeutic vaccines. This exciting about has come about due to the year-on-year growth and are now in a position to bring a talented Validation Specialist to join the team in their Oxford based site. This person will support GMP manufacturing and laboratory facilities by ensuring all aspects of validation (manufacturing & laboratory equipment, facilities and utilities qualification and routine requalification activities, cleaning validation, computerised systems validation and process validation) are complete and up to date. The Validation Team also represent the business in customer audits and regulatory inspections to demonstrate compliant systems. ***What Validation Specialist will do*** + Ensure compliance with regulatory requirements and Quality Management System by supporting/assisting Validation Manager in performing and managing qualification and validation studies of GxP critical systems, equipment and processes. + Generate validation documentation including master plans, validation assessments and test protocols; execute qualification/validation protocols/studies + Ensure Validation Department provides timely, appropriate and expert advice on qualification and validation issues to Manufacturing, QC/QA & Engineering and other company functions as required + Supporting the validation of equipment, facilities, utilities and processes in accordance with GMP requirements and a lifecycle approach in coordination with multi-functional Validation + Represent the Validation Department during client audits and regulatory inspections ***What the Validation Specialist needs*** + Demonstrable validation experience in a biopharmaceutical, pharmaceutical or related industry including Manufacturing/Laboratory Equipment, Facilities & Utilities Qualification (URS, DQ, IQ, OQ & PQ) + Broad knowledge of biopharmaceutical and pharmaceutical industry regulations and guidelines including GMP, GDP, GLP, GEP + Experience of aseptic processing and cleanrooms highly desirable + Computer Systems Validation (CSV) would be advantageous + Educated to degree level in Science (Biological) ***What the Validation Specialist will get*** + Competitive salary + excellent benefits + Work in a fantastic state-of-the-art facility + Lots of training and development opportunities If this sounds like the perfect role for you, then please get in touch today!

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  • Assistant Product Manager 5/22/2018 12:00:00 AM

    Salary: £32000 Location: HITCHIN

    Assistant Product Manager - Hertfordshire - £30k-£35k + Sales and Marketing + Dermatology + Interviews immediately My client are a well established pharmaceutical company based in Hertfordshire. Due to expansion, they are now seeking a new Assistant Product Manager to join their marketing teams. Youll be responsible for creating eye catching materials for use in trade shows and exhibitions. As such youll need: + Strong Pharma Sales background + Experience selling into the NHS primary care + Interest in Marketing.

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