Biotechnology

  • Group Leader – Molecular Biology 12/6/2017 12:00:00 AM

    Salary: £0 Location: SOUTH WEST

    Group Leader - Molecular Biology - South West My client are looking for an experienced scientist to become their new Team Leader in Molecular Biology. A world leader in cellular and genetics therapy is looking for a passionate scientific professional to manage the range of internal and commercial projects relating to their Molecular Biology department. To be suitable for this role, you must have; * Ph.D in a relevant discipline * Advanced Molecular Biology experience * Experience with viral vector genetics and genetic editing software If this sounds like you, please do not hesitate to get in touch.

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  • Associate Scientist – Gene Editing 12/5/2017 12:00:00 AM

    Salary: £0 Location: SOUTH WEST

    My client are looking for an Associate Scientist to contribute to their Gene Editing Team - South West A world leader in cellular and genetics therapy is looking for a passionate scientific professional to help out with a range of internal and commercial projects focusing on developing the current gene editing capabilities. To be suitable for this role, you must have; * BSC or MSC in a relevant discipline. * Strong Mammalian cell culture and Molecular Biology experience * Experience with viral and lentiviral research * Experience with gene editing tools. If this sounds like you, please do not hesitate to get in touch.

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  • Group Leader- Cell Line Development 11/21/2017 12:00:00 AM

    Salary: £55000 Location: OXFORD

    GROUP LEADER - CELL LINE DEVELOPMENT- Oxford- up to £55k Based in Oxfordshire, my client is one of the market leaders in Gene, Cell and biological research. Due to successful growth and development, an exciting opportunity has risen for an experience Group Leader in Cell Line Development. Working with in a Purpose-built facility you will be involved in a range of internal platform development and commercial projects, focusing on establishing cell line development processes in mammalian cells for the production of both therapeutic proteins and viral vectors for gene therapy applications. You will need- A Ph.D or DPhil in a relevant life sciences discipline, along with several years industry experience. • Significant experience in commercial cell line development environment (ideally with HEK and CHO cell lines), and preferably in implementation of new/novel platforms • Experience in managing teams, both via direct line management and through matrix management • Ability to work under demanding conditions, and to cope with shifting priorities • Good understanding of regulatory requirements for the generation of cell lines for biomanufacturing Great Salary- up to £55,000 (dependant on experience) Fantastic development opportunities

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  • QA Manager 11/10/2017 12:00:00 AM

    Salary: £80000 Location: WELWYN GARDEN CITY

    GCP QA Manager- Bio Pharm- Hertfordshire/ Cambridge- Permanent Closing date for this role is 27th November 2017. Based in Hertfordshire/ Cambridge my client is a therapeutics company specialising in world-class technology in structure-based drug design for areas such as CNS and Oncology. Due to continued growth, they are currently looking for an experienced GCP Quality Assurance Manager to join and lead their team. The successful candidate will be will be working with colleagues internally and externally across a range of disciplines to develop and maintain the company’s development quality management systems, to establish inspection readiness and to ensure internal GCP compliance. You will be responsible for all the companies GCP related issues ranging from training, CAPAs, non-compliance issues, auditing, Vendor oversight, Trial Master File audits etc. You will have – At least 5 years’ experience in a hands-on GCP QA role within Pharmaceutical/CRO Experienced GCP auditor capable of conducting vendor audits, investigator site audits, Trial Master File audits etc Fantastic salary (Dependant on experience) Excellent benefits Great career opportunities The company is currently based in Welwyn Garden City, and will be relocating to the Cambridge area in July 2018.

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  • Scientists/ Senior Scientists - Product Development 11/7/2017 12:00:00 AM

    Salary: £0 Location: MOTHERWELL

    My clients mission is to develop and commercialise innovative cell-based products to treat disease, improving patient health and Quality of Life. A clinical development company based in Scotland, with a cell-based product pipeline capable of treating a variety of disorders including cancer and severe viral infections. My client is currently conducting Phase II/III clinical studies of its lead product, in renal cell cancinoma, non-small cell lung cancer and melanoma patients. The Role A number of openings have arisen for Scientists/ Senior Scientists to join an emerging cancer immunotherapy company developing cell based treatments for cancer and severe viral infections. Based at their manufacturing facility in the central belt of Scotland, this role will form part of the product development team. The successful candidate will report directly to the Head of Development. You will form an integral part of the process development team and will provide specialist immunology/oncology knowledge and apply this expertise to the design and development of key assays and protocols. You will troubleshoot and optimise cell culture processes and contribute to the establishment of novel cell culturing processes, both theoretically and practically, with the intention of creating new cell therapy products. One of the main responsibilities, is the development of genetically modified immune cells using (for example) lentiviral transduction techniques with the aim to develop new cell therapy products. You will contribute scientific ideas to aid the product development team in achieving their aims. Perform the identified experiments designed to refine all aspects of the production process and accompanying assays. Key experimental procedures will include but are not limited to cell isolation, cell culture, cell transfection/ transduction, flow cytometry, Luminex, cell-based assays, cell population enrichment and molecular biology techniques such as miRNA/RNA isolation and quantitative RT-PCR. Responsibilities • Perform cell culture of primary immune cells, cancer cells and immortalised cell lines • Perform functional cell based assays such as cytotoxicity assays and proliferation assays. • Design and perform multiparameter flow cytometry experiments • Perform immunological assays such as Luminex and intracellular cytokine assays • Perform lentiviral transduction experiments of various immune cells • Participate in the design, production and optimisation of new lentiviral vectors for use in research projects. • Perform molecular biology techniques, including but not limited to primer design, miRNA and RNA isolation and quantitative PCR assays. • Carry out literature reviews /collate information to identify information useful for the development of novel assays or the improvement of current processes. • Maintain documentation to appropriate quality standards, including, but not limited to, laboratory notebooks, standard operating procedures, COSHH/BIOCOSHH assessments and Risk Assessments. • Provide support to other departments such as quality control. • Analyse independently data generated from experiments, draw appropriate conclusions and decide upon next steps. • Contribute to written documentation including SOPs, publications and patent applications. • Ensure work is performed in accordance with the Company’s QA and Health and Safety policies including the provision of COSHH/BIOCOSHH/Risk assessments. • Analyse and interpret data generated from experiments, drawing appropriate conclusions and deciding upon next steps • Supervise junior members of the product development team The Candidate • Degree in immunology/cell biology/oncology or equivalent. PhD level education is advantageous and is required for any senior scientist posts. • Extensive experience in cell culture, cell based assays and flow cytometry • Experience in transduction of primary cells using lentivirus based methods or transfection of primary cells using non-viral transfection methods. • An interest in cell based therapies and their application to treat cancer and viral/bacterial infections • Experience in molecular biology techniques (e.g. RNA isolation, qPCR) • Experience in writing papers, SOPs, patent applications • Strong presentation skills • Excellent communication and interpersonal skills • Supervisory skills/experience • Ability to work under pressure, as part of a team with a “can do” attitude • Computer skills (Word, Excel, Powerpoint and FlowJo) Salary is negotiable on experience ----- Do you have a desire to succeed and a drive to excel? Then contact Kieran Whittaker for a confidential discussion on: - Tel: 0161 923 8174 Email: Kieran.whittaker@wearenorthpoint.com

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  • Systems Validation Project Leader 11/6/2017 12:00:00 AM

    Salary: £0 Location: BIRMINGHAM

    Validation Team Lead - Biotech - Midlands - £35k My client is a leading international Medical Diagnostics business. Due to there continued expansion they are looking to hire a Team Leader for their validation team. The ideal candidate for this position should have significant experience working within biotechnology or the NHS with experience of SOP analysis, validation for QA/RA and audit. The successful candidate will benefit from; + £35k salary + Excellent Benefits Package + Great Career Opportunities

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  • Senior Scientist - Downstream 10/30/2017 12:00:00 AM

    Salary: £0 Location: OXFORD

    Based in the South East, my client are gowing and extremely successful pharmaceuitcal company focussed on developing life changing treatments for serious diseases. They have expanded from around 80 people in 2014 to over 250 currently, and are continuing to expand due to a number of extremely high-profile contracts won over the last 18 months. The company are currently looking for a large number of candidates. Currently they are looking for a downstream process scientist with the following skills; + Bsc in relevant biolgoical or life-sciences degree + Extensive experience working downstream process based roles within GMP based biopharmaceuticals company. + Experience of protein purification. + Experience of AKTA, ideally using UNICORN + Extra points for: FACS, western-blot, qPCR. The client are offering up to around ~35k for the role and are interviewing currently.

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  • QA Manager 10/26/2017 12:00:00 AM

    Salary: £0 Location:

    The Client My client is a world leading CRO on antibody discovery, engineering, characterization and production. It provides services to Big Pharma companies and top biotech’s from the U.S., Europe and Japan. Its state of the art facilities are located in Porto, Portugal. The role As a Quality Assurance Manager, you are responsible for implementing and maintaining the Quality Assurance Program and to expand its reach to attain GxP. Your main tasks and responsibilities are: • Maintain the proper documentation structure • Evaluate the performance of the organization regarding the Quality Policy Knowledge and Skills To expand its Quality Assurance team, my client is seeking a Quality Assurance Manager, with the following characteristics: • You have a Bachelor/PhD in the relevant field • You have several years of Quality Assurance experience • You have an excellent command of the English language • You have experience as a team leader • You have excellent organization skills • Experience with GLP/GMP is preferred The Benefits • Integration in a highly motivated team • Working in an international environment • Bonus incentives • Career development • Significant tax breaks may apply if you are a foreign or Portuguese expat Do you want to take the next step in your career and join a world leading company? Then contact Kieran Whittaker for a confidential discussion on: - Tel: 0161 923 8174 Email: Kieran.whittaker@wearenorthpoint.com

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  • Senior Antibody Discovery Scientist 10/25/2017 12:00:00 AM

    Salary: £0 Location: PORTUGAL

    Senior Antibody Scientist - Portugal My client are a leading Antibody CRO providing services to the largest pharmaceutical and biotechnology companies around the world. They are looking for a Senior Antibody Scientist to head up and design an antibody discovery programme to better service their clients. As a senior member of the team you will have; * PhD in a relevant field * Molecular Biology Experience * Excellent command of the English Language * Willingness to relocate to Portugal [significant tax breaks applicable]

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  • Technical Services Engineer 9/19/2017 12:00:00 AM

    Salary: £18 Location: ABINGDON

    Technical Services Engineer- Oxfordshire- Contract (Initial 6-month contract to be made permanent) My client is a global leader in the design, manufacture and distribution of medical devices. Due to sustained growth, they are currently looking to take on a technical service engineer with experience of working in the medical devices sector (or similar). You will be responsible for maintaining, repairing, calibrating, and upgrading equipment in line with company standards and client SLA’s. You will also be required to provide internal support to colleagues on the use of equipment as well as technical support via a range of media, to support and gauge clients’ needs. This role will predominately be based on site; however, some occasional UK/ International travel may be required. You will have- A minimum of ONC / HNC in Electronics and Electrical engineering qualification (or similar) Experience of working with Medical devices or similar Strong customer service skills Valid driving license and Valid Passport Fantastic salary £35,000 Excellent working environment Initial 6-month contractor role with the option to be permanent.

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