Biotechnology

  • Group Leader within AAV Vectors 5/23/2018 12:00:00 AM

    Salary: £60000 Location: Oxford

    Based in Oxford our client is a leader in synthetic biology and are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. They are recruiting for a large number of positions at present and are interested in qualified candidates to fill their group leader role within the AAV vectors division. The Group Leader will be involved in a range of internal platform development and commercial projects, predominantly focused on establishing novel AAV vectors, stable viral packaging cell lines/bioproduction systems, and running a commercial batch production function through a sub-team. The company have a number of on-going programmes and collaborations in this area, and multiple government supported grant awards, which the recipient will contribute towards. Prior experience in engineering AAV vectors is essential, as is a detailed knowledge of AAV vector biology, production and characterisation methodologies. Group Leaders are expected to take a scientific and technical leadership role, while providing support and training to Scientists and technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Candidate should have experience in the following; + PhD/DPhil in relevant discipline, with significant experience (>4 years) + Experience working in a commercial/industry environment is preferred but not essential + Demonstrated people management ability, through supervision and development of junior colleagues + Strong network within AAV research and/or commercial arena + Extensive track record of handling a range of adherent and suspension mammalian cell lines + High-level knowledge and experience of viral vector engineering, production and characterisation, with a focus on AAV + Good experience with analytical techniques including flow cytometry/FACS, qPCR, ELISA, HPLC Salaries for the role are expected to be in the 50-65k range.

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  • Associate Scientist in Antibody Discovery 5/23/2018 12:00:00 AM

    Salary: £27000 Location: Oxford

    Based in Oxford our client is a leader in synthetic biology and are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. They are recruiting for a large number of positions at present and are interested in qualified candidates to fill their group leader role within the AAV vectors division. The Associate Scientist will be involved in a range of internal platform development and commercial projects, predominantly focused on expanding antibody discovery technologies and platforms. My client has several on-going programmes in this area, and multiple government supported grant awards, towards which the recipient will contribute. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Prior experience in generating antibody candidates from libraries, particularly in the context of mammalian display is particularly desirable, as is subsequent expression, characterisation and profiling of lead molecules. Salaries are expected to be in the 25 to 28k range dependent on experience.

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  • Senior Microbiologist 5/23/2018 12:00:00 AM

    Salary: £33000 Location: Warrington

    My client is a fast growing microbiological services company, and is recruiting for a Senior Microbiologist/Virologist to join its rapidly expanding and dynamic team. The post holder will enable the delivery of microbiological services to current and prospective clients, on time and on budget. As a customer focussed company, our client needs to maintain a high level of professionalism and timeliness and this role will help in delivering on those aims. The post holder will work within a dynamic and enthusiastic microbiological team. The successful individual will support the laboratory team. They will be involved in the provision of staff training in line with internal SOPs and will support other Senior Microbiologists and Laboratory Microbiologists to deliver projects in line with client requirements. The post holder will check reports written by other staff. The post holder will provide key scientific support to the Laboratory Manager and Microbiologists. The post holder will present data/information/reports at appropriate meetings. The successful candidate will be involved in research and development programmes that support the service side of the business. The post holder may be required to produce scientific literature and present data at conferences and client meetings throughout the UK and abroad. Quality Salaries are expected to be in the 26-33k range.

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  • QC Technologist 5/23/2018 12:00:00 AM

    Salary: £25000 Location: Salisbury

    My client is a leading developer and manufacturer of life saving pharmaceutical therapeutics and vaccines. The client performs a range of breakthrough production, quality and development roles within the pharmaceutical production process. The client is now looking to strengthen their quality control unit by hiring a QC Technologist who will play an incremental part in the company’s strategy. The role will centre around the microbiological QC analyses to support the client’s production and validation programmes. The client is looking for an effective communicator who has GMP experience and can work to a high standard in a microbiology environment. The candidate would ideally need to be highly organised as well as the ability to work within a team. Pharmaceutical industry experience is desirable. Salary: £22,000 - £25,000 Pension scheme 30 days annual leave This is a fantastic opportunity to join a unique company that strives for breakthrough results.

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  • Head of Bioinformatics 5/22/2018 12:00:00 AM

    Salary: £90000 Location: MANCHESTER

    Based in Manchester, my client helps world-leading research companies & scientists solve the most difficult biomedical challenges of today. Their technology uses AI and human biomedical expertise to tie together mostly unused sources of knowledge (‘dark data’) to enrich our understanding of biomedicine. We are a small, but growing team and are searching for extremely talented individuals who’ll join us in our mission. You will have years of top experience working as a bioinformatician, most likely after completing a PhD, although this could have been gained from a commercial setting. Most importantly, you must demonstrate that you’re either at or approaching the peak of your career and are ready to apply these skills in a challenging environment where your work will have a direct impact on our success. Candidates must have most of the following; + Are an expert problem solver, with a strong portfolio of existing research. + Are driven by a desire for quality, pragmatic, a continuous learner & critical thinker. + Have vast experience of one of systems biology, network biology and drug discovery + Are stats mad, with the ability to use R, Matlab or any other popular statistics platform. + Proficient at script writing (Python etc.). We have a separate software engineering team. + Comfortable writing and assisting with grants and publications. + Are able to design research projects from scratch. We love to experiment. Perks: + Competitive pay. We have a large ceiling for top applicants. + Options (employee share scheme). + Talented team to work alongside. + Located in the Manchester Science Park with excellent inner and outer city transport links. + Broad, modern tech stack. + Ability to work with some of the world’s leading biomedical research companies to drive the development of the therapeutics of the future. + Creativity & innovation strongly encouraged & rewarded. + Recent investment, clear roadmap and highly motivating work with an opportunity to make a real difference to biomedical developments.

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  • Analytical Scientist 5/14/2018 12:00:00 AM

    Salary: £38000 Location: SOUTH WEST

    Based in Oxford, our client is a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. They are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are currently in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of their development as a company. They are currently looking for an Analytical Scientist. The suitable candidate will be involved in a range of internal platform development and commercial projects, predominantly focused on establishing analytical processes and methodology for protein and viral vector-based biotherapeutics. Our client has a number of on-going programmes in this area, and multiple government supported grant awards, which the recipient will contribute towards. This will be a predominantly lab-based position and will work closely with the Cell Line Development and Process Development teams to define and design projects. An ability to rapidly assimilate information and to learn new techniques and approaches is essential, as is high-level attention to detail and scientific rigour. Experience in developing multiple analytical techniques and authoring SOPs is absolutely required. Relevant techniques include qPCR, ELISA, Western blotting, SPR and HPLC (Affinity, SEC). Knowledge of automation approaches for analytical methods, and implementation of sample tracking systems is particularly desirable. Salaries for the role are expected to be in the 35 to 40k range.

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  • Field Application Scientist 5/14/2018 12:00:00 AM

    Salary: £32000 Location: WELWYN GARDEN CITY

    Field Application Scientist - Hertfordshire- Permanent- up to £32,000 My client is a specialist Biotech firm developing platforms for testing and developing therapeutics for human diseases. Due to continued growth, they are looking for a Field Application Scientist, with a solid background in bio-engineering, bio-tech, bio-chem or molecular/ cell biology, to help support their pre and post sales activities on their cutting-edge Organ-on-a-Chip platform. You will be responsible for interfacing on an international basis between the clients/ potential clients and the company, to provided technical input and training in order to highlight the benefits and potential of the company’s products. This includes providing presentations, running workshops and building relationships. You will have- •BSc/ MSc, with 3 years industry experience or PhD with experience in a bio-engineering, bio-technology bio chemistry or molecular/ cell biology field •Experience in cell culture and general lab procedures is essential •Ability to travel unrestricted through Europe and the UK (Full UK Driving license required) (Additional European language desirable but not essential) Fantastic salary (to be discussed at application) Great benefits

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  • QA Officer 5/14/2018 12:00:00 AM

    Salary: £25000 Location: BRADFORD

    The Client My client is a knowledge based, science led business focused on delivering the expertise and capabilities their clients demand. Working in the pharmaceutical, biotechnology, food, environmental, agrochemical, petrochemical, chemical and consumer products sectors. They support drug discovery and development in the pharmaceutical and biotechnology markets, by providing testing and specialist analytical services and consultancy to the food and environmental sectors. They also provide toxicology services to the agrochemical, consumer products, chemical and pharmaceutical industries and materials chemistry services to the petrochemical industry. The Role The Quality Assurance Officer’s function is the independent Good Laboratory Practice (GLP) monitoring of work conducted on site. As the Bradford site conducts work to Good Manufacturing Practices Regulations (GMP) this role will have the opportunity to cross train in GMP auditing. Responsibilities • Participate in reviewing Study Plans where required. • Schedule and conduct all audits as assigned. • Write up findings of Quality Assurance Audits and Inspections. • Report all audit findings to management and Study Director/Principal Investigator (as applicable). • Prepare and issue Quality Assurance Statements. • Write and review Quality Assurance Standard Operating Procedures. • Review Standard Operating Procedures for compliance with principles of GLP, as required. • Prepare and conduct computer validation audits. • Participate in scheduling and conducting external audits. • Review forms, where required. • Train other personnel in all aspects of Quality Assurance Systems and Procedures as required. • Advise management of any deficiencies in Regulatory Requirements. • Host or partake in Sponsor and Regulatory visits as appropriate. • Liaise with site personnel to ensure a full understanding of regulatory requirements. • Participate and perform administrative tasks as required. Salary is negotiable on experience ----- Are you prepared to begin a new chapter in your career? If so, this could be the role for you! For more information and a confidential discussion, please contact Kieran Whittaker on: - Tel: - 0161 923 8174 Email: - Kieran.whittaker@wearenorthpoint.com

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  • Senior Design Engineer -IVD medical devices 5/14/2018 12:00:00 AM

    Salary: £50000 Location: MANCHESTER

    The Client My client offers an affordable, real-time PCR system that can serve as the basis for rapid detection, quantification, or drug resistance testing of infectious diseases and pathogens, such as TB or Hepatitis. As they further develop their Point of Care philosophy through product development and refinement, they have an opportunity to reach millions of people who currently have limited access to existing diagnostic technology. Ultimately, their goal is to change lives through rapid access to the benefits of molecular diagnostics. The Role Due to a ramp up of their focus on delivering affordable point of care in vitro molecular diagnostics for addressing global infectious disease challenges, my client are looking to strengthen their product engineering team with the addition of an experienced industrial design engineer to support the HCV and TB IVD consumable plastic/ fluidic device programmes; enhancing their system for future success and global impact. Responsibilities • Mechanical/industrial design, prototyping, design verification and manufacturing transfer and component verification • Acting as the industrial design subject matter expert, working closely with programme managers and outsource industrial design innovation companies, contributing to concept development, design transfer oversight, part verification and whole system validation • Leading design history creation including origination of 3D assembly models, schematics, BOMs, material specifications and verification protocols within an ISO 13485 product design and manufacturing environment • Working closely with cross-functional teams of R&D scientists, electronic and software engineers in product design specification, human factors, user experience and FMEA • Supporting internal Operations and outsourced manufacturing teams in process development, validation and incoming goods QC/ component checking • Support Quality/Regulatory teams with CAPA, out-of-spec/non-confirming product investigations on company mechanical/ consumable parts • Maintain good, clear communication with Managers and Directors. Salary is negotiable on experience ----- Are you prepared to begin a new chapter in your career? If so, this could be the role for you! For more information and a confidential discussion, please contact Kieran Whittaker on: - Tel: - 0161 923 8174 Email: - Kieran.whittaker@wearenorthpoint.com

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  • Antibody Scientist 5/14/2018 12:00:00 AM

    Salary: £40000 Location: SAFFRON WALDEN

    + Great Senior or Research level role + Phage library construction and validation My client are a biotechnology company located in Cambridgeshire specialising in providing protein engineering services for the discovery, identification and design of new peptide, protein and antibody compounds. You will need to evidence a deep understanding of antibody selection, engineering and characterisation within a pharmaceutical or biotechnology company and have a resume which includes as much of the following as possible: • Antibody selection using phage and/or other in vitro display systems • ELISA and Alphascreen or HTRF, affinity determination (BIAcore, Octet) and protein stability assays • Mammalian cell culture experience, including cell line maintenance, transfection, selection and cloning. • Analytical flow cytometry (FACS) background, including experiment controls selection, instrument use and data processing/reporting Youll benefit from a great basic salary and chance to make a real difference in this exciting company.

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