Biotechnology

  • Innovation Officer 6/5/2018 12:00:00 AM

    Salary: £45000 Location: Cambridge

    Based in Cambridgeshire my client is a leading biotech company specialising in Gene editing platform technology. Due to expansion they are currently looking to take on an Innovations Officer to join a diverse and energetic team. You will be responsible for liaising with the company on matters of technology transfer, IP and Patent searches. You must be approachable, friendly and have a confident manner. Ideally you will have; + PhD in Life Sciences subject (i.e Biology, Genetics, Virology, Immunology, bioinformatics etc) + Knowledge of technology transfer and Patent Searches + Basic understanding of IP The company offers great career progression and a starting salary around the £45k mark.

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  • Senior Scientist (ADG) 6/5/2018 12:00:00 AM

    Salary: £37500 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit a senior scientist within their ADG team. Candidates should have the following skills and experiences; + Minimum BSc Degree in Life Sciences/Science/Analytical Science or equivalent level qualification in these disciplines + A good research and development background in quantitative PCR and/or protein analysis. + Practical industry experience in analytics and development projects/activities + Experience of working in GMP-like environments + Use of automation in qPCR work flows. + Development and improvement of analytical methods for lentiviral characterization + A strong background in assay development and automation + Good level of communication and presentation skills + Demonstrated ability to work independently as well as in a team + Ability to undertake projects to agreed timelines and adapt to rapid changes in project priorities Salaries are expected to be in the 35-38k range.

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  • Senior Downstream Processing Scientist 6/5/2018 12:00:00 AM

    Salary: £45000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are currently helping them to recruit a senior downstream scientist within their process, research and development team. Candidates will be recognized experts in downstream processing including bioprocess design, protein expression and purification. They will be primarily involved in purifying and characterizing a variety of therapeutic candidates in support of projects from early stage research to pre-clinical programs. Process, Research and Development works with the companies research teams involved in vector and cell engineering to ensure the seamless transfer of processes from research to manufacturing. The scope of work may include, but are not limited to vector purification, novel purifications, purification process development and verification, technology assessment, data analysis and project reporting. The individual must have a demonstrated ability to work independently and to manage multiple projects either through direct supervision or in collaboration with the programme team. The individual must be innovative and creative, show initiative, collaborative ability and have good general science management skills. Applicants are expected to have excellent time management skills, with the ability to adapt to rapid changes in projects priorities and meeting aggressive timelines. The individual should also enjoy working in a team setting and be able to work well with both research scientists and as well as external collaborators. Salaries for the senior downstream processing roles are expected to be in the 40 to 45k range.

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  • Analytical Scientist (PR&D) 6/5/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit an analytical scientist within their process, research and development team. Candidates should have the following skills and experiences; + An undergraduate degree (or equivalent-level qualification) in a Life Sciences or Biotechnology-related subject + Good aseptic techniques + Knowledge of general cellular and molecular biology laboratory techniques + Practical experience of a range of bioprocess analytical techniques (such as cell-based assays, FACS based assays, nucleic acid extractions, qPCR, SDS PAGE, Western blot analysis, ELISA, HPLC, etc.) + The ability to work in a high paced team environment and to, meet challenging deadlines + Demonstrated ability to work independently as well as in a team setting + Strong written and verbal skills Salaries are expected to be in the 35-38k range.

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  • Senior Analytical Scientist in Process, Research and Development 6/5/2018 12:00:00 AM

    Salary: £42000 Location: Oxford

    Our client is a leading biopharmaceuticals organisation based from state-of-the-art offices in Oxford. Having rapidly expanded over the course of the last 3 years to over 300 employees, they are currently recruiting a wide range of biotechnology based positions. The company are at the forefront of the gene and cell therapy sector, having built a novel drug development platform which they leverage to develop products both in-house and with partners. Their proprietary portfolio of products include a lead product for Parkinson’s disease. With preparations completed for this to move into the clinic, they are in active discussions with a number of third parties to potentially out-licence the product, thereby sharing the costs and the risks whilst retaining an interest in the value of the product as it progresses. Other products at development stage include a gene-based therapies for corneal graft rejection and cancer. The company have a very respected name in the industry, and offer potential candidates a strong career path, generous financial renumeration, and a caring yet focussed environment in which to flourish. We are helping them to recruit a senior analytical scientist for their process, research and development department. Candidates should have experience with the following; + Bsc in Life-sciences or biotechnology related subject. + Strong aseptic techniques + Knowledge of general cellular, and molecular biology techniques + Practical experience of a range of bio-process analytical techniques such as cell based assays, FACS, nucleic acid extractions qPCR, SDS< Western blot, ELISA + Strong written and verbal skills Salaries for the roles are expected to be in the 38-42k range.

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  • The Senior Scientist – Cell Line Development 6/5/2018 12:00:00 AM

    Salary: £40000 Location: Oxford

    Based in Oxfordshire, my client is one of the market leaders in Gene, Cell and biological research. Due to successful growth and development, an exciting opportunity has risen for an experience Group Leader in Cell Line Development. Working with in a Purpose-built facility you will be involved in a range of internal platform development and commercial projects, focusing on establishing cell line development processes in mammalian cells for the production of both therapeutic proteins and viral vectors for gene therapy applications. You will need; + A Ph.D or DPhil in a relevant life sciences discipline, along with several years industry experience. + Significant experience in commercial cell line development environment (ideally with HEK and CHO cell lines), and preferably in implementation of new/novel platforms + FACS, AKTA, PCR preferably in a GLP/GMP environment + Ability to work under demanding conditions, and to cope with shifting priorities Good understanding of regulatory requirements for the generation of cell lines for biomanufacturing Great Salary & Benefits along with fantastic development opportunities.

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  • Scientist in Gene Editing 6/5/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    Based in Oxford, our client is a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. They are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are currently in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of their development as a company. The Gene Editing Scientist will be involved in a range of internal platform development and commercial projects, predominantly focused on expanding gene editing capabilities and platforms. My client has a number of on-going programmes in this area, and multiple government supported grant awards, which the recipient will contribute towards. Scientist colleagues are expected to drive and lead specific projects and areas of research from the bench, while providing support and training to Technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Candidate should have the following skills; + Msc or PhD/DPhil in relevant discipline (MSc should be associated with minimum 2-3 years relevant laboratory experience) + Experience of using gene editing platforms (including CRISPR) + Experience working in a commercial/industry setting is preferred but not essential + Extensive mammalian cell culture experience. Salaries are expected to be in the 35-40k range.

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  • Scientist – Lentiviral vectors 6/5/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    My client are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. We are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of our development as a company. The Scientist – Lentiviral Vectors will be involved in a range of internal platform development and commercial projects, predominantly focused on Lentiviral vector engineering, and establishing stable viral packaging cell lines and associated processes. They have a number of on-going programmes and collaborations in this area, and multiple government supported grant awards, which the recipient will contribute towards. Scientist colleagues are expected to drive and lead specific projects and areas of research from the bench, while providing support and training to technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Candidates should have; + PhD/DPhil in relevant discipline, or MSc with significant experience (>4 years) + Experience working in a commercial/industry environment is preferred but not essential + Extensive track record of handling a range of adherent and suspension mammalian cell lines + Knowledge and experience of viral vector engineering, production and characterisation, with a focus on Lentivirus + Good experience with analytical techniques including flow cytometry and qPCR Salaries are expected to be around the 28-38k mark.

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  • Scientist- AAV Production 6/5/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    Based in Oxford my client who are a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. We are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are currently looking for a scientist in their AAV Production team who will manage an internal function for the generation and characterisation of AAV vectors for both in-vitro and in-vivo applications (non-GMP). The appointee would work to expand this service within the company and would then be responsible for its operational delivery working with technician colleagues. This function would sit within the AAV Vector Group, which addresses both viral vector engineering and novel-bioproduction methodologies and works with a number of academic and industry collaborators. Candidate should have the following skills; + Prior experience in generating and characterising AAV vectors is essential. + Relevant techniques (see next section) include plasmid preparation, transfection (hyperflask/stack, cell factories, suspension), harvest/clarification, purification by iodixanol, CsCl, affinity, IEX, and characterisation by qPCR, ELISA, Western blot. Salaries are expected to be in the 35-38k range.

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  • Post Doc - Upstream Scientist 6/5/2018 12:00:00 AM

    Salary: £35000 Location: Cambridge

    Upstream Process Scientist - Cambridgeshire - £35k My client is an innovative biotech firm looking at new antibiotic technologies. They are expanding their teams and are looking for an Upstream Process Scientist. Youll be responsible for upstream development in flasks and bioreactors, scale-up activities, QC analysis and impurity monitoring. Youll be responsible for analysing and reporting on all studies. There will also be the opportunity for European travel with work. Youll need a PhD in a relavent life science and good experience of bacterial fermentation. You should have experience in microbiology, aseptic processing, good maths skills, and ideally experience in bacterial fermentation and / or bacteriophage.

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