Biotechnology

  • NGS Scientist, Cancer R&D 8/30/2018 12:00:00 AM

    Salary: £35000 Location: Kidlington

    My client are a gene and cell therapy company based in Oxfordshire. Due to a fantastic growth period they are looking for an ambitious, talented and motivated Scientist with experience in molecular biology/ genetics, specifically dealing with NGS, DNA-seq, RNA-seq, Meth-Seq, and whole genome sequencing, to be responsible for a variety of lab-based projects. You will have: A minimum of a MSc and several years industry experience or a PhD in Molecular Biology/ Biochemistry/Genetics based subject. Detailed experience of Next Generation Sequencing, including but not limited to targeted DNA-seq, RNA-seq, Meth-Seq, and whole genome sequencing Commercially focused – ability to interact with high profile research scientists and corporate customers Salary: up to £35,000 (depending on experience) Great Benefits Fantastic development options

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  • Program Manager 8/24/2018 12:00:00 AM

    Salary: £90000 Location: SAFFRON WALDEN

    Program Manager The Client My client is a leader in providing NGS technologies for some of the world’s most innovative and market disrupting companies. Working on ground breaking projects, unlocking the hidden potential of the human genome and collaborating with key strategic partners are all part of their path to success and they are now looking to recruit a talented Program Manager to helm one of their major projects. The Role As a Program Manager you will drive key strategic programs towards the implementation of Genomic Medicine into mainstream healthcare. One of the key initiatives will be to implement a new workflow in lab operations and software integration and driving down turnaround time by supporting a very fast turnaround service. Responsibilities • Manage a large cross-functional program of strategic importance to Illumina • Manage plans for resource needs, scope, budget and quality targets to deliver to key milestones communicating to the customer and across Illumina • Creates and manages the overall project schedule, including identification of keys tasks and establishing realistic timelines with durations, dependencies, critical path, and milestones • Working closely with the Quality Management System within the ILS team • Ensure compliance to relevant ISO standards (13485 and 14971) • Identify needs for plan changes, then track and communicate plan changes to the team and stakeholders to ensure program goals are in alignment with business objectives • Schedule, prepare content for executive committee presentations, and present as required • Identify and manage program risks, remove obstacles, and facilitate trade-offs to enable successful project completion • Share best project management practices with others in to improve organizational efficiency and effectiveness ----- For more information and a confidential discussion, please contact Kieran Whittaker on the below: - Tel: 0161 923 8174 Email: Kieran.Whittaker@wearenorthpoint.co.uk

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  • Deputy Head of Engineering & Facilities 8/22/2018 12:00:00 AM

    Salary: £59000 Location: Stevenage

    Deputy Head of Engineering & Facilities-Hertfordshire Based in Hertfordshire, my client is a leading global biologics company, looking for a Deputy Head of Engineering, to be responsible for managing the day to day facilities management, mechanical & electrical engineering. You will have: BSc or equivalent in an Engineering or another relevant technical area Proven experience of working within a GMP Engineering/Facilities management team in commercial biologicals, vaccines, cell or gene therapies manufacturing facility ideally within a large multifunctional site. Experience of working with commercial clients and collaborators Knowledge of EU GMP and FDA regulatory requirements Knowledge of applicable Environmental and Health and Safety legislation within the pharmaceutical / biopharmaceutical industry Proven understanding of Building Services, M&E systems, building fabric and BMS, EMS systems and operation Proven first-hand experience of working with both paper based and Electronic PPM Systems Fantastic salary: up to £60,000 (depending on experience) Excellent career development opportunities Great benefits

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  • Qualified Person 8/20/2018 12:00:00 AM

    Salary: £0 Location: Stevenage

    The Client My client, based in Stevenage, are specialists in helping Cell and Gene therapy companies translate early stage research into quality, commercially viable, scalable and investable therapies. With a team of over 120 Cell and Gene therapy experts and state-of-the-art development and viral vector labs, my client has ensured they remain a Centre of Excellence in this field. The Role The Qualified Person (QP) will participate in the translation of strategic direction into a Quality framework that defines, directs and governs the tactical application of GMP compliance for the Manufacturing Centre. In the first instance, this will be predominantly focused on developing and supporting the delivery of a fit for purpose Quality Management System and providing practical quality subject matter expertise to both CGT and collaborating residents (“Collaborators”). This activity will be required to support the initial grant of the facility MIA and MIA(IMP), and then to support on-going operations. The Manufacturing Centre hosts Collaborator manufacturing activities. You will perform batch certification for Collaborator manufacturing activities, as required, and act as a QP for the Manufacturing Centre. Responsibilities • Direct report to the Head of QA with close interaction with the Manufacturing Centre Management Team • Provide subject matter expertise in quality assurance, aseptic manufacturing and environmental microbiology to Manufacturing Centre staff and Collaborators • Ideally, act as Site Microbiologist, otherwise provide expert advice on Annex 1 requirements by approving the facility environmental monitoring, gowning and cleaning regimes. • Provide expert advice for microbiology changes and deviations and coach QC staff on microbiology as required (note: line management of the microbiology laboratories is not a part of this job specification) • Ensure the QMS is fit for purpose for a multi-purpose, multi-client facility, and maintain processes to ensure site compliance to the QMS • Maintain processes for batch certification for Collaborators and perform batch certification of ATMPs and or ATIMPs for Collaborators • Perform QP approval of Manufacturing Centre data (e.g. environmental monitoring data) to support certification by Collaborator QPs, Product Quality Reviews etc. • Develop and maintain QP to QP Agreements, as required, with Collaborator QPs • Represent the Manufacturing Centre as a QP, to external regulators, inspectors and Collaborators • Participate in the preparation and management of regulatory agency and client inspections, including co-hosting as required. Salary is negotiable on experience ---- For more information and a confidential discussion, please contact Kieran Whittaker on the below: - Tel: 0161 923 8174 Email: Kieran.Whittaker@wearenorthpoint.co.uk

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  • Bioinformatics – NGS Data Analysis 8/10/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    The company I am hiring for is a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a focus on viral vectors for gene therapy applications. I am looking for an experienced and self-motivated bioinformatician to design, implement and run software pipelines for analysing next-generation sequencing (NGS) data. The successful applicant will be located within purpose-fitted laboratories at the Oxford Science Park. ***What the Bioinformatician will do*** + Build state-of-the-art data processing pipelines for targeted re-sequencing, whole genome sequencing, genome editing, and differential expression analysis experiments + Support our wet lab scientists in the planning, and interpretation, evaluation and visualisation of results for investigations with an NGS component + Stay up-to-date with new developments, technologies and methods in NGS data analysis, and proactively seek out collaborations with our group leaders to develop and extend our intellectual property portfolio in this area ***What the Bioinformatician will need*** + MSc/BSc in bioinformatics, computational biology, computer science or a related field, or equivalent experience in a biotechnology research environment + Programming experience with one or more of Python, Perl, Java and R, and familiarity with associated numerical analysis libraries (e.g. NumPy for Python, ND4J for Java, ect.) + Analysis experience with NGS datasets (preferably Illumina paired-end, PacBio or Nanopore) in DNA-seq, RNA-seq, break-seq, GUIDE-seq or similar contexts ***What the Bioinformatician will need get*** + Competitive Salary up to £38,000 + Work in state-of-the-art facility and sector + Excellent benefits & training opportunities If this sounds like the perfect role for you, then please get I touch today!

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  • Research Assistant (Discovery I (Host) Team) 8/7/2018 12:00:00 AM

    Salary: £28000 Location: Aberdeen

    Based in Aberdeen, my client a pharmaceutical company focussed on developing several biotherapeutics based on the human gut microbiome. They are currently looking for candidates for their research assistant position and are seeking candidates with the following skills; + Degree or Higher National Certificate in molecular biology, biomedical sciences, or other science-related discipline (preferably at MSc level) or at least 3 years’ experience working in an industrial environment in a similar role + Competency in cell culture techniques, including isolation and culture of primary cells from tissue samples (e.g. gut, spleen) and human specimens + Competency in immunological techniques (e.g. flow cytometry, ELISA, Bead Arrays) + Ability to keep accurate and detailed records of produced results + Good organisational and communication skills + Experience with basic microbiology techniques would be desirable Salaries for the position are expected to be up to around 28k.

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  • Research Assistant- (Discovery II Host Team) 8/7/2018 12:00:00 AM

    Salary: £28000 Location: Aberdeen

    Based in Aberdeen, my client a pharmaceutical company focussed on developing several biotherapeutics based on the human gut microbiome. They are currently looking for candidates for their research assistant position and are seeking candidates with the following skills; + BSc Degree or Higher National Certificate in molecular biology, microbiology, biomedical sciences, or other science-related discipline + Experience with cell culture techniques + Experience in a variety of basic immunological laboratory techniques, including nucleic acid extraction and qPCR + Ability to keep accurate and detailed records of produced results + Good organisational and communication skills The role offers excellent chance to progress with an internationally renowned organisation. Salaries for the position are expected to be in the 25-28k area with additional benefits.

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  • Post Doc Upstream Scientist 7/26/2018 12:00:00 AM

    Salary: £35000 Location: Cambridge

    My client is a leading biotechnology company developing novel drugs for the treatment of bacterial infections, to address the serious issue of increased antibiotic resistance worldwide. Due to current expansion they are currently hiring for a research upstream scientist to join the team, with a working knowledge and practical experience with cell cultures and cell banking. Position: Senior Upstream Fermentation Scientist – Biotechnology company based in Cambridge. Perfect first position in industry for a PHD with a strong focus on Microbial Fermentation, bioprocessing, Upstream etc. Expanding biotech conducting cutting edge research in antibiotic resistance Key focus on development in role. The line manager is keen to bring on a PHD candidate and focus on training and development. 1. Design, develop and optimise bacterial fermentation processes suitable for manufacturing. 2. Work with production methods such as shake flasks, 1L Glass bioreactors up to 15L scale stainless steel fermentation systems. 3. Ensure laboratory notebooks and/or Batch Manufacturing Records are completed and maintained according to Standard Operating Procedures (SOP). 4. To form part of multidisciplinary teams working within all areas of the Process Development team, and provide results, data and progress to project leaders. Role requirements: To be successful in your application to this exciting opportunity as the Fermentation Scientist we are looking to identify the following on your profile and past history: 1. Proven industry experience in developing and/or optimising methods for biopharmaceutical manufacturing. 2. Relevant PhD and extensive laboratory experience in a Life Science discipline such as Biochemistry, Biotechnology, Biochemical Engineering etc. as well as experience of working to a GMP biopharmaceutical environment.

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  • Scientist, Phage Selections 7/24/2018 12:00:00 AM

    Salary: £50000 Location: Cambridge

    Based in Cambridge my client is a market leader in bio-therapeutics. Due to continued growth the company are looking to develop a new pipeline of products targeted to oncology and inflammatory diseases and are looking for Senior Scientist in Phage Selections to join their team. You will be responsible for designing and carrying out phage display selections, screening and characterisation of outputs in order to identify lead Affimer therapeutic candidates. You will have: Essential skills and previous experience •MSc or higher in protein biochemistry/molecular biology with a minimum of 2-4 years’ laboratory experience or equivalent. •A minimum of 2 years’ laboratory experience of working in the field of in vitro display technologies (one or more of phage display, ribosome display, yeast display etc.) •A high level of lab-based competency in molecular biology, manipulating DNA and creating expression constructs. •Experience of characterising protein-protein interactions using at least two of the following methods; ELISA, HTRF, cell-based assays, SPR or BLI Salary from £30,000- £50,000 depending on experience Fantastic career opportunities State of the art facilities

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  • Product Steward 7/24/2018 12:00:00 AM

    Salary: £0 Location: Oxford

    Product Steward- Oxfordshire- Biotechnology- UP to £50k Based in Oxfordshire, my client is a world leader in Gene and Cell Therapy technologies. Due to a fantastic period of growth they have an exciting opportunity for a motivated and experienced Product Steward to join their team. You will be responsible for product stewardship, managing the continued process verification for the clinical/ commercial products and technical oversight of each products’ process performance and capability as well as maintaining oversight of post-approval CMC changes to ensure consistency and a timely implementation. You will also Act as a single point of contact for internal stakeholder and strategic partner queries regarding the products as well as leading the root cause investigations into process excursions (OOS/OOE/OOT) including CAPA implementation. You will have: BSc or higher in a life science, biotechnology, chemical engineering or another related discipline A strong track record and knowledge of bioprocess development, scale-up and GMP manufacturing (including large scale mammalian cell culture support) Significant experience in GMP manufacturing/ manufacturing science and technology/technical development/Quality Excellent analytical, organisational and problem-solving skills Fundamental understanding of standard pharmaceutical analytical testing Expert in reviewing and writing technical reports. Great salary: up to £52,000 (dependant on experience) Fantastic career development opportunities

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