Biotechnology

  • The Senior Scientist – Cell Line Development 6/5/2018 12:00:00 AM

    Salary: £40000 Location: Oxford

    Based in Oxfordshire, my client is one of the market leaders in Gene, Cell and biological research. Due to successful growth and development, an exciting opportunity has risen for an experience Group Leader in Cell Line Development. Working with in a Purpose-built facility you will be involved in a range of internal platform development and commercial projects, focusing on establishing cell line development processes in mammalian cells for the production of both therapeutic proteins and viral vectors for gene therapy applications. You will need; + A Ph.D or DPhil in a relevant life sciences discipline, along with several years industry experience. + Significant experience in commercial cell line development environment (ideally with HEK and CHO cell lines), and preferably in implementation of new/novel platforms + FACS, AKTA, PCR preferably in a GLP/GMP environment + Ability to work under demanding conditions, and to cope with shifting priorities Good understanding of regulatory requirements for the generation of cell lines for biomanufacturing Great Salary & Benefits along with fantastic development opportunities.

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  • Scientist in Gene Editing 6/5/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    Based in Oxford, our client is a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. They are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are currently in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of their development as a company. The Gene Editing Scientist will be involved in a range of internal platform development and commercial projects, predominantly focused on expanding gene editing capabilities and platforms. My client has a number of on-going programmes in this area, and multiple government supported grant awards, which the recipient will contribute towards. Scientist colleagues are expected to drive and lead specific projects and areas of research from the bench, while providing support and training to Technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Candidate should have the following skills; + Msc or PhD/DPhil in relevant discipline (MSc should be associated with minimum 2-3 years relevant laboratory experience) + Experience of using gene editing platforms (including CRISPR) + Experience working in a commercial/industry setting is preferred but not essential + Extensive mammalian cell culture experience. Salaries are expected to be in the 35-40k range.

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  • Scientist – Lentiviral vectors 6/5/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    My client are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. We are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are in a phase of rapid expansion and are seeking highly motivated and enthusiastic scientists and engineers to join the team and help facilitate the next stage of our development as a company. The Scientist – Lentiviral Vectors will be involved in a range of internal platform development and commercial projects, predominantly focused on Lentiviral vector engineering, and establishing stable viral packaging cell lines and associated processes. They have a number of on-going programmes and collaborations in this area, and multiple government supported grant awards, which the recipient will contribute towards. Scientist colleagues are expected to drive and lead specific projects and areas of research from the bench, while providing support and training to technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Candidates should have; + PhD/DPhil in relevant discipline, or MSc with significant experience (>4 years) + Experience working in a commercial/industry environment is preferred but not essential + Extensive track record of handling a range of adherent and suspension mammalian cell lines + Knowledge and experience of viral vector engineering, production and characterisation, with a focus on Lentivirus + Good experience with analytical techniques including flow cytometry and qPCR Salaries are expected to be around the 28-38k mark.

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  • Scientist- AAV Production 6/5/2018 12:00:00 AM

    Salary: £38000 Location: Oxford

    Based in Oxford my client who are a leader in synthetic biology, is a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. A unifying theme across the portfolio is expertise in DNA design, expression system optimisation, cell line development and engineering of viral delivery systems. We are located within purpose-fitted laboratories at the Oxford Science Park, just South of Oxford. They are currently looking for a scientist in their AAV Production team who will manage an internal function for the generation and characterisation of AAV vectors for both in-vitro and in-vivo applications (non-GMP). The appointee would work to expand this service within the company and would then be responsible for its operational delivery working with technician colleagues. This function would sit within the AAV Vector Group, which addresses both viral vector engineering and novel-bioproduction methodologies and works with a number of academic and industry collaborators. Candidate should have the following skills; + Prior experience in generating and characterising AAV vectors is essential. + Relevant techniques (see next section) include plasmid preparation, transfection (hyperflask/stack, cell factories, suspension), harvest/clarification, purification by iodixanol, CsCl, affinity, IEX, and characterisation by qPCR, ELISA, Western blot. Salaries are expected to be in the 35-38k range.

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  • Post Doc - Upstream Scientist 6/5/2018 12:00:00 AM

    Salary: £35000 Location: Cambridge

    Upstream Process Scientist - Cambridgeshire - £35k My client is an innovative biotech firm looking at new antibiotic technologies. They are expanding their teams and are looking for an Upstream Process Scientist. Youll be responsible for upstream development in flasks and bioreactors, scale-up activities, QC analysis and impurity monitoring. Youll be responsible for analysing and reporting on all studies. There will also be the opportunity for European travel with work. Youll need a PhD in a relavent life science and good experience of bacterial fermentation. You should have experience in microbiology, aseptic processing, good maths skills, and ideally experience in bacterial fermentation and / or bacteriophage.

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  • Team Leader in Library Design 6/5/2018 12:00:00 AM

    Salary: £55000 Location: Saffron walden

    Team Leader - Library Design, Cambs, up to £60k + Management role at well-established Biotech + Antibody libraries + Interviews immediately My client are a biotechnology company located in Cambridgeshire specialising in providing protein engineering services for the discovery, identification and design of new peptide, protein and antibody compounds. We are seeking a confident Team Leader to head up an NGS platform to support lead discovery projects and line manage a small team. Youll need to evidence: + PhD / equivalent and line management + Next Generation Sequencing (NGS) for library manufacturing + Lead discovery using display technologies

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  • Patent Officer 6/4/2018 12:00:00 AM

    Salary: £33000 Location: Oxford

    Based in Oxford our client is a leader in synthetic biology and are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. They are recruiting for a large number of positions at present and are interested in qualified candidates to fill their patent officer role. The main duties of the role are as follows; + To enable the company to develop a cost-effective patent portfolio and to maximise opportunities to fund the company’s product and services development road-map via grant funding + Taking over work initially performed in other areas of the business and liaising extensively with the company’s Research and Development employees and the CFO + Identification of opportunities for new patent or grant applications + Drafting and filing applications for grants, patents, trademarks etc. + Collating and recording cost, labour time and other relevant data + Prior art searching + Patent renewal management Candidate should have; + Experience in a similar role dealing with Patent administration + Strong communication and organisational skills + A qualification in Grant or Patent administration is desirable but not essential Salaries for the role are competitive and are expected to be around the 28-33k range.

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  • DMPK Scientist 6/4/2018 12:00:00 AM

    Salary: £50000 Location: Cambridge

    Based in Cambridge, my client is a world leader at bringing innovation into Oncological and Neurological drug discovery. With several exciting prospects in clinical development - the company are seeking a Senior DMPK Scientist to Lead Projects and team members in a challenging scientific environment. You will have; + PhD in a relevant biopharmaceutical area, Oncology/Neurological; + Significant experience of pharmacokinetic drug discovery + ADMET, PK/PD models and preclinical skills would all be a huge advantage in this position. If you are looking for a new challenge in a truly competition beating environment with a fantastic package and progression structure – then do get in touch with an agent today.

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  • Principal Product Development Scientist 5/29/2018 12:00:00 AM

    Salary: £50000 Location: WELWYN GARDEN CITY

    Principal Product Development Scientist My client is an award-winning clean technology company that has industrialised the process of recycling biomaterials for industry use. Due to continued development they are looking to take on an enthusiastic, dedicated and hands-on, Principal Product Development Scientist to lead a small team of scientists, Creating new flavours & fragrances and functional oil-based bio-chemical products from waste bio-materials. You will have: A MSc or PhD in Chemistry, food science or a related, relevant discipline. At least 7 years industry experience in New Product Development within the flavour & fragrance, food & beverage or other relevant industry sector, with experience of formulation equipment and processing Experience of presenting to large audiences and networking at relevant external events Experience of developing, coaching and leading other scientists and work colleagues Salary- Dependant on experience- up to £50,000 Great development opportunities The company’s head office is based in central London, with their scientific facility-based Welwyn Garden City’s, BioPark. The Principal Product Development Scientist will be based in the laboratory at the BioPark but it wouldn’t be unusual to be travelling across locations.

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  • Group Leader within AAV Vectors 5/23/2018 12:00:00 AM

    Salary: £60000 Location: Oxford

    Based in Oxford our client is a leader in synthetic biology and are a specialised contract research organisation offering services to support the discovery, development and production of biologics, with a particular focus on viral vectors for gene therapy applications. They are recruiting for a large number of positions at present and are interested in qualified candidates to fill their group leader role within the AAV vectors division. The Group Leader will be involved in a range of internal platform development and commercial projects, predominantly focused on establishing novel AAV vectors, stable viral packaging cell lines/bioproduction systems, and running a commercial batch production function through a sub-team. The company have a number of on-going programmes and collaborations in this area, and multiple government supported grant awards, which the recipient will contribute towards. Prior experience in engineering AAV vectors is essential, as is a detailed knowledge of AAV vector biology, production and characterisation methodologies. Group Leaders are expected to take a scientific and technical leadership role, while providing support and training to Scientists and technicians working in the group. The position will involve extensive interaction with both internal and external stakeholders, and the ability to show commitment to scientific development and innovation are considered essential. Candidate should have experience in the following; + PhD/DPhil in relevant discipline, with significant experience (>4 years) + Experience working in a commercial/industry environment is preferred but not essential + Demonstrated people management ability, through supervision and development of junior colleagues + Strong network within AAV research and/or commercial arena + Extensive track record of handling a range of adherent and suspension mammalian cell lines + High-level knowledge and experience of viral vector engineering, production and characterisation, with a focus on AAV + Good experience with analytical techniques including flow cytometry/FACS, qPCR, ELISA, HPLC Salaries for the role are expected to be in the 50-65k range.

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